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Table 1 Clinical and biochemical data of the studied groups

From: Adiponectin: an adipocyte-derived hormone, and its gene encoding in children with chronic kidney disease

 

CT

MHD

Controls

 

(n = 32)

(n = 46)

(n = 70)

Age

9.14 ± 7.59

10.62 ± 3.49

10.7 ± 4.51

Gender (M/F)

15 (46.88%) /17(53.12%)

25(54.35%) /21(45.65%)

40(57.14%) /30(42.86%)

BMI(kg/m2)

17.64 ± 1.17

18.89 ± 3.00

20.88 ± 1.50

SBP (mmHg)

98.66 ± 6.66

127.13 ± 18.37 b*

94.55 ± 9.80

DBP (mmHg)

64.66 ± 6.67

85.15 ± 13.76 b*

60.59 ± 10.11

Creatinine (mg/dl)

3.93 ± 3.75 a*

6.32 ± 1.55 b*

0.77 ± 0.34

Predialysis urea, (mg/dl)

51.12 ± 10.45 a*

71.56 ± 20.61 b*

7.80 ± 2.64

eGFR, ml_min_1 _1.73m2

15.41 ± 1.76 a**

11.30 ± 3.35 b**

87 ± 8.9

Dialysis, Yrs

 

2.75 ± 1.59

 

Nephropathies:

   

Hereditary nephropathies

0

17

 

renal hypoplasia or dysplasia

14

2

 

obstructive uropathies

8

6

 

neurogenic bladder

4

2

 

Glomerulopathy

0

2

 

Unknown

4

17

 

Metabolic

2

0

 

Antihypertensive drugs:

   

α-adrenoceptor antagonists

2

2

 

ß-blockers

0

9

 

ACE inhibitors

6

17

 

Ca channel blockers

10

29

 

Kt/V

 

1.69 ± 0.42

 

Total cholesterol (mg/dl)

164.44 ± 50.10

193.04 ± 51.37 b*

160.31 ± 18.74

Triglycerides (mg/dl)

160.78 ± 57.33 a**

147.00 ± 66.98 b**

65.31 ± 18.35

HDL cholesterol (mg/dl)

21.35 ± 1.17a*

27.34 ± 9.88 b*

39.55 ± 7.94

hs-CRP, mg/dl

3.04 ± 3.24

3.62 ± 3.97 b*

1.36 ± 0.67

IL6(pg/ml)

59.50 ± 46.48 a*

19.10 ± 23.68 b**

3.17 ± 1.56

Adiponectin (μg/ml)

154.00 ± 7.18 a**

52.44 ± 19.1 b**

24.80 ± 8.23

  1. Data was evaluated by ANOVA test. Values are presented as means ± SD or percentage as applicable. CT conservative treatment, MHD maintenance hemodialysis, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, ACE angiotensin converting enzyme, Kt/V adequacy of hemodialysis, hs-CRP high sensitivity c-reactive protein. a*P < 0.05 or a**P < 0.01vs. control and MHD b*P < 0.05 or b**P < 0.01 vs. control and CT .