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Figure 1 | BMC Research Notes

Figure 1

From: Akt and phospholipase Cγ are involved in the regulation of growth and migration of MDA-MB-468 breast cancer and SW480 colon cancer cells when cultured with diabetogenic levels of glucose and insulin

Figure 1

Western blot analysis of Akt and PLCγ expression. Western blot analysis was performed to evaluate Akt and PLCγ expression and shows that Akt expression was up-regulated in both cell lines when additional glucose was available (A). The combination of glucose and insulin caused an even higher up-regulation in both cell lines (A). PLCγ expression showed considerable increase in SW480 colon cancer cells exclusively (B). Numbers indicate relative Akt and PLCγ expression levels in relation to β-actin, whereby expression levels in the 5.5 mM glucose control media were set to 100%.

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