Table 1 Phases of the MRC framework[27]in the PalliPA study*
Current study | Planned future work | ||||
|---|---|---|---|---|---|
Phase | 0 | I | II | III | IV |
MRC framework description | Preclinical or theoretical (why should this intervention work?) | Modelling (how does it work?) | Exploratory or pilot trial (optimising trial measures) | Definite randomized controlled trial | Implementation |
PalliPA study context | Existing evidence: German guideline “Informal caregivers”, results from international implementation and intervention studies, results of caregivers’ needs assessments | Workshops: GPTs are informed about the existing evidence and discuss individual strategies for identifying and relieving burdened caregivers | Participatory action research: individual strategies are implemented in the practices and refined within a Plan-Do-Study-Act cycle | Not part of the PalliPA study | Not part of the PalliPA study |
Estimation of effects on caregivers and patients as a basis for the planning of a subsequent trial | |||||