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Table 1 Definitions of oncologists’ reasons for not recommending chemotherapy

From: Reasons physicians do not recommend and patients refuse adjuvant chemotherapy for stage III colon cancer: a population based chart review

Reasons oncologists did not recommend adjuvant chemotherapy

Definition

Medical complications of surgery

Any medical incident during or just following surgery (e.g. myocardial infarction, stroke)

Surgical complications of surgery

Any surgery related complication (e.g. delayed wound healing, wound infection, abscess)

Co-morbidities

A medical condition or chronic disease preceding the onset of cancer and perceived by oncologist as a contraindication for chemotherapy (e.g. coronary heart disease, heart failure, kidney or liver failure)

Frailty/Performance status

Generalized weakness or poor physical performance status

Pharmacological concern

Potential drug-drug interaction between the adjuvant chemotherapeutic regimens and other drugs a patient is using for a chronic or incidental medical condition.

Potential complication or adverse event of chemotherapy in a susceptible patient (e.g. vasospasm in a patient susceptible to coronary heart disease)

No social network or support

Lack of social, emotional, or physical support

Age

Patient age was the reason or one of the reasons for not recommending chemotherapy

Disease progression

Progression of the cancer to stage IV by the time the patient had a consultation with the oncologist and/or prior to receiving post-surgical treatment

Other

Reasons stated other than those listed above (e.g. non-conclusive staging at the time of consult)

Unclear

Reason(s) for not recommending chemotherapy are vague and not clearly stated