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Table 7 Minimal inhibitory concentration (MIC) of antibiotics in absence and presence extracts Tetrapleura tetraptera (μg/ml)

From: Antibacterial and antibiotic-potentiation activities of the methanol extract of some cameroonian spices against Gram-negative multi-drug resistant phenotypes

Bacterial strains Antibiotics and MIC in absence and presenceTetrapleura tetraptera extract
Ampicillin Cefepime Chloramphenicol Ciprofloxacin Cloxacillin
Alone MIC/2.5 MIC/5 Alone MIC/2 MIC/5 Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5
AG100Atet - - - - - - 256 256 (1) I - 256 128 (2) S 128 (2)S - - -
AG102 - - - 128 256 (0.5)I 256 (0.5) I 16 8 (2) S 8 (2) S <2 <2 <2 - - -
CM64 - - - - - - nt nt nt nt nt nt - - -
KP63 - - - 256 256 (1) I - - 256 (>1) S 256 (>1) S 64 64 (1) I 64 (1) I - 128 (>2) S 256 (>1) S
PA124 128 64 (2)S 128 (1)I 128 128 (1)I 128 (1) I 32 4 (8) S 8 (4) S 16 16 (1) I 16 (1) I - - -
Bacterial strains Erythromycin Kanamycin Norfloxacin Streptomycin Tetracycline
Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5
AG100Atet 64 64 (1) I 64 (1) I - 256 (>1) S 256 (>1) S 128 128 (1) I 256 (0.5) I <2 <2 <2 2 2 (1) I 2 (1) I
AG102 32 64 (0.5) I 64 (0.5) I <2 <2 <2 <2 <2 <2 - 256 (>1) S 256 (>1) S <2 <2 <2
CM64 - 256 (>1) S - 4 4 (1) I 8 (0.5) I 4 4 (1) I 8 (0.5) I 32 16 (2) S 32 (1) I nt nt nt
KP63 16 <1 (>16) S 8 (2) S 32 32 (1) I 64 (0.5) I - 256 (>1) S - <4 <4 <4 <2 <2 <2
PA124 128 64 (2) S 64 (2) S 128 64 (2) S 64 (2) S 64 32 (2) S 64 (1) I nt nt nt 8 2 (4) S 2 (4) S
  1. MIC/2.5: concentration of plant extract added equal to 204.8 μg/mL for CM64 and to 409.6 μg/ml for AG100ATET. PA124. KP63. AG102.
  2. MIC/5: concentration of plant extract added equal to 102. 4 μg/mL for CM64; and to 204.8 μg/ml for AG100ATET.PA124. KP63. AG102.
  3. (): Folds decreasing of MIC. S: synergy. I: indifference. nt: not tested; (−): MIC > 256 μg/ml.