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Table 3 Values of correlation (‘r’) of parasitological and clinical parameters with survival of animals subjected to different treatment schemes using biotherapic (BIOT Tc 17dH )

From: Highly diluted medication reduces parasitemia and improves experimental infection evolution by Trypanosoma cruzi

‘r’ FOR CORRELATION

PARAMETERS

CI

BIOTPI

BIOT4PI

AUC

(-)0.2250

(-)0.1980

(-)0.2349

Ptotal

(-)0.3220

(-)0.4387

(-)0.5227

Pmax

(-)0.2989

(-)0.3182

(-)0.5350

Day Pmax

NS

NS

NS

PPP

(+)0.4825

(+)0.6704

(+)0.9995

PP

(+)0.7901

(-)0.7000

(-)0.8998

Ta

NS

NS

NS

WEIGHT

NS

NS

(+)0.4797

WATER

NS

NS

NS

  1. NS = no significant correlation. ‘r’ values are presented for significant correlations (p < 0.05) between survival and the parameters: AUC = area under the curve (parasites/mL); Ptotal – total parasitemia (parasites/ mL); Pmax = maximum peak of parasites (parasites/ mL); Day of Pmax- Day of maximum peak of parasites; PPP = Prepatent period; PP = patent period; Ta = Temperature; Weight and Water. Groups: CI: control group – infected animals treated with 7% ethanol-water solution diluted in water (10μL/mL) offered ad libitum; BIOTPI: infected animals treated with biotherapic BIOTTc 17dH diluted in water (10μL/mL) offered ad libitum from the day of the infection until the death of the animals; BIOT4PI: infected animals treated with biotherapic BIOTTc 17dH diluted in water (10μL/mL) offered ad libitum from the 4th day of the infection until the death of the animals.