Skip to main content

Table 5 Cytokine and immune mediator concentrations in amniotic fluid by maternal age

From: Influence of maternal age, gestational age and fetal gender on expression of immune mediators in amniotic fluid

Mediator Age Age Age Age Age p-value
19-25 26-30 31-35 36-40 >40
IL-2 (n = 66) 5.2 4.6 4.3 3.8 3.9 0.97
IL-4 (n = 182) 8.3 6.6 9.0 9.2 9.7 0.18
IL-6 (n = 156) 879.2 668.9 738.7 669.2 832.8 0.97
IL-8 (n = 185) 829.5 551.4 754 621.0 552.1 0.45
IL-10 (n = 161) 9.1 7.1 5.8 5.5 5.1 0.49
IL-12 (n = 161) 5.1 5.8 4.9 5.3 5.5 0.94
IL-15 (n = 173) 35.8 31.3 28.0 12.3 11.5 0.51
IL-17 (n = 66) 32.7 19.3 19.2 23.4 21.8 0.46
TNF- α (n = 161) 9.3 11.0 12.1 13.0 12.1 0.56
GRO- α (n = 184) 629.5 1254.3 1228.1 663.0 492.9 0.01
Pro IL1-ß (n = 157) 19.8 19.5 16.9 19.4 17.0 0.48
Histone (n = 161) 0.3 0.2 0.3 0.3 0.3 0.83
IP-10 (n = 169) 1435.3 644.6 722.7 814.0 702.8 0.33
MIP1-ß (n = 182) 27.5 25.8 28.3 25.9 27.7 0.71
MIP1- α (n = 186) 25.6 25.9 25.7 24.8 26.0 0.79
  1. Median biomarker concentration (pg/ml) by maternal age.