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Table 4 Clinical characteristics of patients in the MADIT II trial

From: Improved survival of patients with coronary artery disease and low ejection fraction with ICD implantation versus conventional therapy in a real world survey

  MADIT II ICD + MADIT II ICD –
(n = 742) (n = 490)
  Prior myocardial infarction more than 28 days ago and an EF ≤ 30%
Age (years) 64 ± 10 65 ± 10
Female Gender (%) 16 15
LVEF (% ± SD) 23 ± 5 23 ± 6
Pharmacotherapy   
Betablockers (%) 70 70
ACE inhibitors 68 72
Antiarrhythmics 16 14
Diuretic 72 81
Statins 67 64
Mean follow-up 20 months
Total mortality 14.2 19.8
HR Total mortality HR 0.69 (95%CI 0.51-0.93); p = 0.016
Heart failure related hospitalization 19.9 14.9
  1. Legend: HR, hazard ratio; CI, confidence interval, EF, ejection fraction; LV, left ventricular.