Table 4 Clinical characteristics of patients in the MADIT II trial
MADIT II ICD + | MADIT II ICD – | |
|---|---|---|
(n = 742) | (n = 490) | |
Prior myocardial infarction more than 28 days ago and an EF ≤ 30% | ||
Age (years) | 64 ± 10 | 65 ± 10 |
Female Gender (%) | 16 | 15 |
LVEF (% ± SD) | 23 ± 5 | 23 ± 6 |
Pharmacotherapy | ||
Betablockers (%) | 70 | 70 |
ACE inhibitors | 68 | 72 |
Antiarrhythmics | 16 | 14 |
Diuretic | 72 | 81 |
Statins | 67 | 64 |
Mean follow-up | 20 months | |
Total mortality | 14.2 | 19.8 |
HR Total mortality | HR 0.69 (95%CI 0.51-0.93); p = 0.016 | |
Heart failure related hospitalization | 19.9 | 14.9 |