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Table 1 Which of the following signs and symptoms make you suspect PID?

From: Attentiveness of pediatricians to primary immunodeficiency disorders

  Percent answered “yes”
Persistent oral thrush 97
Infections with uncommon organisms 96
Failure of infant to thrive 90
Sepsis with atypical mycobacteria 83
Severe dermatitis 81
Two invasive deep seated infections 80
Delayed wound healing 79
Death of a sibling in infancy 77
Absent tonsils 75
Autoimmune cytopenia 65
Partial albinism 65
Lymphoma 64
Otitis media (5 bouts per year) 62
Interrupted aortic arch 62
Pneumonia (2 bouts per year) 59
Severe warts 57
Severe periodontitis 55
Polyendocrinopathy 48
Dextrocardia * 45
Transfusion reaction 44
Malar rash * 28
Inguinal lymphadenopathy * 22
Polydactaly * 20
Ventricular septal defect * 9
  1. *Does not increase likelihood of PID.
  2. (The order of the items is presented according to the percentage picked by respondents, not how it appeared in the questionnaire).