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Table 3 Mean results, incremental effects, costs, cost-effectiveness ratio and Incremental Cost-Effectiveness Ratio (ICER)

From: Scenario drafting to anticipate future developments in technology assessment

Model scenario

time

Mean value parameter

Δeffects*

Δcosts*

ICER

  

failure

NC

uptake

   

Start

2005

0.27

0.35

0.03

0.0010

€ 1,940

€ 1,9 mill

Separate scenarios

Failure

2010

0.20

Idem

Idem

0.0011

€ 2,094

€ 1,9 mill

2020

0.08

Idem

Idem

0.0013

€ 2,385

€ 1,9 mill

Non-compliance

2010

Idem

0.26

Idem

0.0011

€ 1,939

€ 1,7 mill

2020

Idem

0.08

Idem

0.0013

€ 1,940

€ 1,5 mill

Uptake

2010

Idem

Idem

0.50

0.0592

€ 1,547

€ 26,145

2020

Idem

Idem

0.92

0.1089

€ 1,211

€ 11,123

Combined scenarios

2005

0.27

0.35

0.03

0.0010

€ 1,940

€ 1,9 mill

2010

0.20

0.26

0.50

0.0728

€ 1,630

€ 22,388

2020

0.08

0.08

0.92

0.1492

€ 1,171

€ 7,853

  1. Δeffects: Incremental effects of 70-gene signature compared to the Adjuvant Online, Δcosts: Incremental costs of 70-gene signature compared to the Adjuvant Online, ICER: Incremental cost-effectiveness ratio, NC: non compliance.