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Table 3 Allele frequencies of the NR1H4 variants in the study population and the allele association analysis

From: Association of genetic variation in the NR1H4 gene, encoding the nuclear bile acid receptor FXR, with inflammatory bowel disease

SNP rs3863377 (G → A)
Case MAF (%) P OR CI Reported MAFs 1
non-IBD 32 (2.9)     4.0%
IBD 10 (1.1) 0.004** † 0.37 0.18-0-75  
CD 6 (1.1) 0.015* † 0.36 0.15-0.86  
UC 4 (1.2) 0.075 † 0.38 0.14-1.10  
SNP rs56163822 , (G →T)
Case MAF (%) P OR CI Reported MAFs 1
non-IBD 20 (1.7)     2.2%
IBD 34 (3.2) 0.027* 1.86 1.06-3.25  
CD 20 (2.9) 0.081 1.74 0.93-3.25  
UC 14 (3.5) 0.036* 2.07 1.03-4.13  
SNP rs7138843 , (A → T)
Case MAF (%) P    Reported MAFs 1
non-IBD 17 (1.7)     0.9%
IBD 21 (2.4) ns    
CD 11 (2.0) ns    
UC 10 (3.0) ns   
SNP rs10860603 , (G → A)
Case MAF (%)   P   Reported MAFs 1
non-IBD 173 (14.9)     20.5%
IBD 139 (12.9) ns    
CD 90 (13.4) ns    
UC 49 (12.3) ns    
SNP rs35724 , (G → C)
Case MAF (%) P    Reported MAFs 1
non-IBD 466 (40.0)     40.8%
IBD 471 (43.8) ns    
CD 299 (44.4) ns    
UC 172 (43.0) ns