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Table 1 Characteristics of 30 patients with malignant mesothelioma and retreated with pemetrexed-based therapy as second-line therapy

From: Re-challenge with pemetrexed in advanced mesothelioma: a multi-institutional experience

 

N. (%)

N. of patients

30 (100)

Histology:

 

---Epidermoid

28 (93)

---Mixed

2 (7)

Previous surgery:

 

---Palliative pleural decortications

11 (37)

---Extrapleural pneumonectomy

6 (20)

---Videothoracoscopy and pleurodesis

3 (10)

---Other

1 (3)

Never

9 (30)

Median age (years) (range)

64.1 (35–78)

Performance Status (ECOG):

 

---0

15 (50)

---1

15 (50)

Sex:

 

---Female

7 (23)

---Male

23 (77)

Stage at diagnosis (IMIG):

 

---II

9 (30)

---III

8 (27)

---IV

12 (40)

---Other

1 (3)

Combination of first-line chemotherapy:

 

---Cisplatin and pemetrexed

21 (70)

---Carboplatin and pemetrexed

9 (30)

Response to first-line treatment:

 

---Stable Disease

15 (50)

Partial Response

15 (30)