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Table 1 Macroscopic and microscopic findings in lungs of mock-infected pigs and pigs infected with Actinobacillus pleuropneumoniae

From: PR-39, a porcine host defence peptide, is prominent in mucosa and lymphatic tissue of the respiratory tract in healthy pigs and pigs infected with actinobacillus pleuropneumoniae

Pig Infection Day of necropsy after infection Macroscopic lung lesion score[17] Histological findings
1 mock 21 0 Predominantly without pathological findings, small areas with slight interstitial pneumonia
2 mock 21 3.6 Predominantly without pathological findings, small areas with slight interstitial pneumonia
3 mock 21 0 Predominantly without pathological findings, small areas with slight interstitial pneumonia
4 A.pp. serotype 7 strain AP76 1 17.7 Severe purulent and fibrinous pneumonia, moderate interstitial pneumonia
5 A.pp. serotype 7 strain AP76 21 12.3 Severe catarrhal and purulent bronchopneumoniae with abscesses, slight interstitial pneumonia
6 A.pp. serotype 7 strain AP76 21 6.3 Severe purulent pneumonia with abscesses and sequesters with colliquative necrosis
7 A.pp. serotype 7 strain AP76 21 0 Predominantly without pathological findings, small areas with severe interstitial pneumonia
8 A.pp. serotype 7 strain AP76 21 4.4 Moderate catarrhal and purulent bronchopneumonia with abscesses, moderate interstitial pneumonia
9 A.pp. serotype 7 strain AP76 21 0 Most areas without pathological findings, small areas with severe interstitial pneumonia
10 A.pp. serotype 7 strain AP76 4 31.4 Severe purulent and necrotic bronchopneumonia, fibrinous tissue alterations
11 A.pp. serotype 7 strain AP76 21 6.4 Severe purulent pneumonia with fibrotic tissue alterations, moderate interstitial pneumonia