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Table 1 Characteristic differences in expression of 14-3-3 protein isoforms in the different stages of follicular development as observed by immunohistochemical staining of adult mouse ovarian sections

From: Expression of 14-3-3 protein isoforms in mouse oocytes, eggs and ovarian follicular development

Feature Isoform Stage of Ovarian Follicle
   Secondary Early Antral Graafian
Expression in zonae pellucidae around oocytes 14-3-3 β 14-3-3 γ 14-3-3 ε 14-3-3 ζ 14-3-3 η 14-3-3 τ 14-3-3 σ ++ + ++ + - ++ ++ ++ + ++ + - ++ ++ ++ + ++ - - ++ ++
Prominent lack of expression in peripheral mural granulosa cells 14-3-3 β 14-3-3 γ 14-3-3 ε 14-3-3 ζ 14-3-3 η 14-3-3 τ 14-3-3 σ Yes Yes Yes No Yes Yes Yes Yes No No No No No No Yes Yes Yes No No Yes Yes
Marked accumulation in granulosa cells surrounding the antrum 14-3-3 β 14-3-3 γ 14-3-3 ε 14-3-3 ζ 14-3-3 η 14-3-3 τ 14-3-3 σ Yes Yes No No No No Yes Yes Yes Yes Yes Yes Yes Yes
  1. '++' = Considerable expression; '+' = Some expression;
  2. '-' = Non-detectable expression; 'Yes' = Presence of the feature; 'No' = Feature not detectable