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Table 3 Comparison of predictors for OA treatment by NSAIDS with different definitions of responder

From: Clinically important improvement in the WOMAC and predictor factors for response to non-specific non-steroidal anti-inflammatory drugs in osteoarthritic patients: a prospective study

  N (%) AUC P (HL) Predictors OR 95% CI P R2
16% improvement* 92 (53.2) 0.77 0.51 High level of education 3.77 1.12-12.7 0.03 0.34
     No Previous knee injury 4.55 1.46-14.8 0.001  
Both criteria+ 65 (37.6) 0.84 0.53 No Previous knee injury 10.27 2.08-50.6 0.004 0.47
     Knee height 3.34 1.05-10.5 0.040  
     High level of education 3.7 1.01-13.41 0.047  
  1. *Patients with an MCID on the total WOMAC score (16% change)
  2. +Patients who answered "slightly better" or "much better" to the health transition question and have an MCID on the total WOMAC score (16% change)
  3. After adjusting of Age > 57 (years), Body mass index > 31 (kg/m2), Knee height > 49 cm; Joint space width > 3.5 mm; Existence of previous knee injuries; Co morbidities; high level of education (no formal education vs. higher than no formal education); Number of pregnancies > 4; EQ 5D index at baseline > 0.36; VAS EQ 5D at baseline > 40