Clinically important improvement in the WOMAC and predictor factors for response to non-specific non-steroidal anti-inflammatory drugs in osteoarthritic patients: a prospective study

Table 3 Comparison of predictors for OA treatment by NSAIDS with different definitions of responder

	N (%)	AUC	P (HL)	Predictors	OR	95% CI	P	R2
16% improvement*	92 (53.2)	0.77	0.51	High level of education	3.77	1.12-12.7	0.03	0.34
				No Previous knee injury	4.55	1.46-14.8	0.001
Both criteria+	65 (37.6)	0.84	0.53	No Previous knee injury	10.27	2.08-50.6	0.004	0.47
				Knee height	3.34	1.05-10.5	0.040
				High level of education	3.7	1.01-13.41	0.047

*Patients with an MCID on the total WOMAC score (16% change)
+Patients who answered "slightly better" or "much better" to the health transition question and have an MCID on the total WOMAC score (16% change)
After adjusting of Age > 57 (years), Body mass index > 31 (kg/m2), Knee height > 49 cm; Joint space width > 3.5 mm; Existence of previous knee injuries; Co morbidities; high level of education (no formal education vs. higher than no formal education); Number of pregnancies > 4; EQ 5D index at baseline > 0.36; VAS EQ 5D at baseline > 40

ISSN: 1756-0500