Table 1 Summary of genetic models simulated
First model | Second model | ||||||
|---|---|---|---|---|---|---|---|
Simulation | Disease loci | Model type | Level of heterogeneity | Odds ratio | Contribution | Odds ratio | Contribution |
1 | 2 | additive | 25/75 | 1.5 | 25% | 1.5 | 75% |
2 | 2 | additive | 25/75 | 2 | 25% | 2 | 75% |
3 | 2 | additive | 25/75 | 1.5 | 25% | 2 | 75% |
4 | 2 | additive | 25/75 | 2 | 25% | 1.5 | 75% |
5 | 2 | additive | 50/50 | 1.5 | 50% | 1.5 | 50% |
6 | 2 | additive | 50/50 | 2 | 50% | 2 | 50% |
7 | 2 | additive | 50/50 | 1.5 | 50% | 2 | 50% |
8 | 2 | recessive | 25/75 | 1.5 | 25% | 1.5 | 75% |
9 | 2 | recessive | 25/75 | 2 | 25% | 2 | 75% |
10 | 2 | recessive | 25/75 | 1.5 | 25% | 2 | 75% |
11 | 2 | recessive | 25/75 | 2 | 25% | 1.5 | 75% |
12 | 2 | recessive | 50/50 | 1.5 | 50% | 1.5 | 50% |
13 | 2 | recessive | 50/50 | 2 | 50% | 2 | 50% |
14 | 2 | recessive | 50/50 | 1.5 | 50% | 2 | 50% |
15 | 4 | XOR | 25/75 | 1.5 | 25% | 1.5 | 75% |
16 | 4 | XOR | 25/75 | 2 | 25% | 2 | 75% |
17 | 4 | XOR | 25/75 | 1.5 | 25% | 2 | 75% |
18 | 4 | XOR | 25/75 | 2 | 25% | 1.5 | 75% |
19 | 4 | XOR | 50/50 | 1.5 | 50% | 1.5 | 50% |
20 | 4 | XOR | 50/50 | 2 | 50% | 2 | 50% |
21 | 4 | XOR | 50/50 | 1.5 | 50% | 2 | 50% |