Figure 6

Estimated pocket volumes of the binding site for ccrA, IMP-1, VIM, NDM-1 and other B1 MBLs. Boxplots show the distribution of volume for various MBL binding sites; while the plasmid-bourne MBLs (IMP-1, NDM-1, VIM) share similar volume sizes, with fluctuation, ccrA and other B1 MBLs have a distinctly smaller site. Estimates were calculated using CASTp [23]. Data for generating these plots are from Additional file 3.