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Table 1 Demographic and clinical characteristics of all HCC patients and comparison of viral-HCC vs. viral marker negative HCC

From: Hepatocellular carcinoma in Native South Asian Pakistani population; trends, clinico-pathological characteristics & differences in viral marker negative & viral-hepatocellular carcinoma

 

ALL HCC cases

Comparison of viral-HCC vs. viral marker negative HCC mean ± SD/%

n = (645), mean ± SD/%

   
 

Viral-HCC (n = 546)

Viral marker negative HCC (n = 99)

P value

Age(years)

56.93 ± 11.15

56.46 ± 10.85

59.57 ± 12.45

0.01

Gender

    

  Female

29.1

29.9

25.3

0.34

  Male

70.9

70.1

74.7

 

BMI (Kg/m2)

    

  <18

6.2

5.5

10.1

 

  18-22.9

28.1

28.6

25.3

0.24

  23-24.9

23.6

22.9

27.3

 

  ≥25

42.2

43.0

37.4

 

Diabetes Mellitus

    

  No

59.8

61.7

49.5

0.02

  Yes

40.2

38.3

50.5

 

Hypertension

    

  No

65.6

66.8

58.6

0.11

  Yes

34.4

33.2

41.4

 

Dyslipidemia

    

  No

97.5

97.4

98.0

0.74

  Yes

2.5

2.6

2.0

 

Child score

9.29 ± 2.31

9.27 ± 2.29

9.40 ± 2.43

0.59

Child class

    

  A

12.6

12.8

11.1

0.50

  B

42.3

43.0

38.4

 

  C

45.1

44.1

50.5

 

Okuda class

    

  I

14.3

14.3

14.1

0.97

  II

61.4

61.5

60.6

 

  III

24.3

24.2

25.3

 

Complication of CLD

    

  No

25.6

26.2

22.2

0.39

  Yes

74.4

73.8

77.8

 

Hyperspleenism

    

  No

37.8

36.6

44.4

0.14

  Yes

62.2

63.4

55.6

 

Ascites

    

  No

31.5

31.3

32.3

0.84

  Yes

68.5

68.7

67.7

 

PSE

    

  No

65.9

66.8

60.6

0.23

  Yes

34.1

33.2

39.4

 

Esophageal varices

    

  No

47.0

46.3

50.5

0.44

  Yes

53.0

53.7

49.5

 

Upper GI bleed

    

  No

59.5

59.2

61.6

0.64

  Yes

40.5

40.8

38.4

 

Hepatohydrothorax

    

  No

91.0

91.4

88.9

0.43

  Yes

9.0

8.6

11.1

 

Hepatorenal syndrome

    

  No

77.4

77.8

74.7

0.50

  Yes

22.6

22.2

25.3

 

Hepatopulmonary syndrome

    

  No

92.2

92.9

88.9

0.19

  Yes

7.8

7.1

11.1

 

Total Bilirubin(mg/dl)

    

  <2

50.2

50.7

47.5

0.48

  2-3

20.5

20.9

18.2

 

  >3

29.3

28.4

34.3

 

Albumin(mg/dl)

    

  >3.5

8.1

7.7

10.1

0.73

  2.8-3.5

29.3

29.5

28.3

 

  <2.8

62.6

62.8

61.6

 

ALT (IU/ml)

    

  Normal

30.23

28.4

40.4

0.19

  Elevated

69.77

71.6

59.6

 

Prothrombin time(seconds)

    

  No

92.2

92.9

88.9

0.19

  Yes

7.8

7.1

11.1

 

Total Bilirubin(mg/dl)

    

  <2

50.2

50.7

47.5

0.48

  2-3

20.5

20.9

18.2

 

  >3

29.3

28.4

34.3

 

Albumin(mg/dl)

    

  >3.5

8.1

7.7

10.1

0.73

  2.8-3.5

29.3

29.5

28.3

 

  <2.8

62.6

62.8

61.6

 

ALT (IU/ml)

    

  Normal

30.23

28.4

40.4

0.19

  Elevated

69.77

71.6

59.6

 

Prothrombin time(seconds)

    

  <3

42.8

41.6

49.5

0.14

  3-6

34.6

36.1

26.3

 

  >6

22.6

22.3

24.2

 

Platelets counts(10 9 /L)

165.91 ± 107.02

155.72 ± 96.33

222.12 ± 141.01

<0.001

AFP(IU/ml)

    

  ≤200

58.8

58.2

61.6

0.30

  >200

41.2

41.8

38.4

 
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BMC Research Notes

ISSN: 1756-0500

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