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Table 1 Clinical characteristics of the Amish*

From: Polymorphisms in the SOCS7 gene and glucose homeostasis traits

Trait T2DM NGT NGT + IGT
(n = 145) (n = 358) (n = 765)
% female 69.7 48.0 52.6
Age (yrs) 65 ± 12 51 ± 11 44.3 ± 14.7
BMI (kg/m2) 30.1 ± 4.0 27.4 ± 4.7 27.0 ± 4.8
% IGT - - 19.1
Age of onset of DM (yrs) 59 ± 11 - -
HOMA-IR - 2.5 ± 1.5 2.5 ± 1.4
Fasting Glucose (mmol/L) - 5.04 ± 0.42 5.02 ± 0.46
2 hour Glucose (mmol/L) - 5.76 ± 1.20 6.21 ± 1.7
Fasting Insulin (pmol/L) - 68.1 (55.6, 86.8) 66.7 (54.9, 86.1)
2 hour Insulin (pmol/L) - 211.8 (126.4, 341.0) 218.8 (128.5, 364.6)
AUC Glucose (mmol/L) - 349.2 ± 51.5 359.9 ± 67.2
AUC Insulin (pmol/L) - 761.9 (540.3, 1046.6) 752.1 (525.0, 1046.6)
  1. * mean ± SD unless otherwise indicated.
  2. median (25th, 75th percentile).