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Table 3 Few examples revealing differences in the expression profiles based on selection of the most abundant isomiR versus the reference miRNA

From: Analysis of the microRNA transcriptome and expression of different isomiRs in human peripheral blood mononuclear cells

3A)
miRNAs Normal 1 Normal 2
Reference miRNA frequency Most abundant isomiR frequency Reference miRNA frequency Most abundant isomiR frequency
hsa-miR-10a-5p 171 935 195 792
hsa-miR-15b-5p 2266 4355 992 2547
hsa-miR-21-5p 30955 49979 33091 50565
hsa-miR-23a-3p 11160 21009 8375 17718
hsa-miR-26b-5p 3409 28934 3685 23018
hsa-miR-30d-5p 1449 14156 1893 15233
3B)
miRNAs Patient 1 Patient 2
Reference miRNA frequency Most abundant isomiR frequency Reference miRNA frequency Most abundant isomiR frequency
hsa-miR-10a-5p 56 256 99 396
hsa-miR-15b-5p 1835 2342 1187 4114
hsa-miR-21-5p 8868 18032 36712 75907
hsa-miR-23a-3p 5793 11774 8296 16159
hsa-miR-26b-5p 2239 12346 10093 51801
hsa-miR-30d-5p 1638 8012 1619 15705
  1. A) in Normal samples. (B) in Patient samples.