Histologic and immunohistochemical findings. Footnote: a: H&E X 20. Perforation site of small bowel with necrosis and acute and chronic inflammation. b: H&E X 400. Enlarged cells 90o 2/3 contrast with typical CMV inclusions in ulcer. c: Streptavidin-Biotin X 100. A large number of cells are positive for CMV early antigen. d: Streptavidin-Biotin X 400. CMV inclusions are readily identified in cells of the muscularis propria on stain for smooth muscle actin.