|
Responder
|
Non responder
|
---|
n (M/F)
|
8 (5/3)
|
7 (5/2)
|
BMI, kg/m2
|
23.6 ± 4.2
|
26.4 ± 4.1
|
HbA1c(NGSP),%
|
6.8 ± 0.4
|
6.9 ± 0.7
|
HOMA-R
|
1.85 ± 1.18
|
3.90 ± 4.58
|
ISI (Matsuda’s index)
|
9.30 ± 2.35
|
6.15 ± 3.23*
|
Insulinogenic index
|
1.01 ± 0.69
|
0.43 ± 0.30*
|
PI/I ratio
|
0.08 ± 0.06
|
0.13 ± 0.15
|
CPR, nmol/L
|
0.66 ± 0.33
|
0.66 ± 0.33
|
(ng/dL)
|
(2.0 ± 1.0)
|
(2.0 ± 1.0)
|
Total cholesterol, mmol/L
|
5.18 ± 1.21
|
5.54 ± 0.59
|
(mg/dL)
|
(200 ± 47)
|
(214 ± 23)
|
Triglyceride, mmol/L
|
1.19 ± 0.50
|
2.32 ± 1.40*
|
(mg/dL)
|
(106 ± 45)
|
(206 ± 124*)
|
HDL-C, mmol/L
|
1.73 ± 0.51
|
1.16 ± 0.31*
|
(mg/dL)
|
(67 ± 20)
|
(45 ± 12*)
|
- Mean ± SD *P < 0.05 vs responder (paired t-test).
- BMI, body mass index; HbA1c, hemoglobin A1c; NGSP, National Glycohemoglobin Standardization Program; HOMA-IR, homeostasis model assessment of insulin resistance; ISI, insulin sensitivity index; PI/I ratio, proinsulin/insulin ratio; CPR, C-peptide immunoreactivity; HDL-C, high-density lipoprotein cholesterol; IRI, immunoreactive insulin.