Clinical findings associated with homozygous sickle cell disease in the Barbadian population – do we need a national SCD registry?

Table 1 Clinical features associated with HbSS in the Barbadian vs. Jamaican population

Clinical feature	Barbados n = 48	Jamaica n = 1160
Clinical feature	n/N (%)	n/N (%)
Ever painful crisis	45/48 (94)	n/a
# participants who had ≥ 1 pain crisis in the last year	21/48 (44)	216/1160 (18.6)
• 1 crisis	5/21 (24)	119/216 (55.1)
• 2 crises	4/21 (19)	42/216 (19.4)
• 3 crises	1/21 (5)	21/216 (9.7)
• 4 crises	2/21 (9)	16/216 (7.4)
• ≥5 crises	9/21 (43)	18/216 (8)
# painful crises per person in the year	69 crises in 21 people	476 crises in 216 people
Hx chronic leg ulcer	13/48 (27)	53/225 (29.5)
Albuminuria: (urinary protein/creatinine ratio of >30 mg/g)	19/42 (44)	36/85 (42.5)
TRJV ≥ 2.5 m/s	9/32 (28)	n/a

This table shows a) the number (%) of the population who have ever experienced a painful crisis b) the number (%) of the population who experienced a painful crisis within the last year c) the frequency of crises within the last year d) the number of painful crises per person in the last year e)the number (%) of persons with a history of chronic leg ulceration f) the number (%) of persons with albuminuria defined as urine albumin/creatinine ratio of ≥30 mg/g and g) the number (%) of persons with a TRJV ≥2.5 m/s.

ISSN: 1756-0500