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Table 1 Comparison of stroke patients’ characteristics admitted between one month* and over 2 years** and during autumn, winter and summer months***to eight NHS Trusts in the East of England

From: Similarity of patient characteristics and outcomes in consecutive data collection on stroke admissions over one month compared to longer periods

Variables Oct 2009 cohort (n = 308) Full cohort (n = 8398) Autumn cohort (n = 2184) Winter cohort (n = 3478) Summer cohort (n = 2736)
Results p-value§vs. Oct 2009 Result p-value§vs. Oct 2009 Result p-value§vs. Oct 2009 Result p-value§vs. Oct 2009
Age          
n (%) 258 (84) 8280 (99)   2162 (99)   3444 (99)   2674 (98)  
Mean (SD) 78.3 (11.9) 76.3 (13.0) 0.01§ 76.5 (12.7) 0.03§ 76.5 (12.8) 0.02§ 75.9 (n = 2674) < 0.01§
Median (IQR) 80 (72-87) 79 (70-86) 0.19χ 79 (70-86) 0.36χ 79 (69-86) 0.20χ 79 (69-85) 0.11χ
Gender    0.06¥   0.04¥   0.05¥   0.18¥
Female 172 (56) 4121 (51)   1050 (50)   1699 (50)   1372 (52)  
Male 134 (44) 3998 (49)   1057 (50)   1682 (50)   1259 (48)  
Pre-stroke residence    0.60   0.31   0.74   0.47
Home 276 (92) 5231 (90)   1533 (89)   2115 (90)   1583 (89)  
Care home 22 (7) 531 (9)   169 (10)   192 (8)   170 (10)  
Other 3 (1) 69 (1)   12 (1)   37 (2)   20 (1)  
Pre-stroke Rankin    0.07   0.08   0.05   0.13
0 128 (50) 2501 (52)   750 (51)   981 (51)   770 (53)  
1 54 (21) 813 (17)   245 (17)   342 (18)   226 (15)  
2 20 (8) 572 (12)   175 (12)   236 (12)   161 (11)  
3 28 (11) 545 (11)   167 (11)   210 (11)   168 (11)  
4 23 (9) 322 (7)   97 (7)   112 (6)   113 (8)  
5 2 (1) 103 (2)   33 (2)   42 (2)   28 (2)  
Weekend    0.36¥   0.59¥   0.31¥   0.32¥
Yes 84 (27) 2096 (25)   564 (26)   857 (25)   675 (25)  
No 224 (73) 6302 (75)   1620 (74)   2621 (75)   2061 (75)  
Time of admission    0.63¥   0.73¥   0.35¥   0.99¥
0900 to 1700 164 (53) 4045 (48)   1140 (52)   1755 (50)   1458 (53)  
1700 to 0900 144 (47) 4353 (52)   1044 (48)   1723 (50)   1278 (47)  
Prior atrial fibrillation    0.10¥   0.10¥   0.16¥   0.09¥
Yes 68 (35) 1123 (29)   347 (29)   407 (30)   369 (29)  
No 127 (65) 2710 (71)   850 (71)   952 (70)   908 (71)  
Type of stroke    0.23¥   0.06¥   0.36¥   0.43¥
Ischaemic 260 (89) 6533 (87)   1777 (85)   2657 (87)   2099 (88)  
Haemorrhagic 31 (11) 980 (13)   307 (15)   380 (13)   293 (12)  
OCSP classification    0.01¥   0.06¥   0.01¥   0.01¥
LACS 58 (23) 1195 (25)   360 (25)   480 (26)   355 (24)  
PACS 116 (47) 1815 (38)   566 (39)   694 (38)   555 (38)  
TACS 52 (21) 1012 (21)   324 (22)   373 (20)   315 (21)  
POCS 22 (9) 711 (15)   200 (14)   277 (15)   234 (16)  
NIHSS          
n (%) 46 (15) 1843 (22) <0.01§ 584 (27) <0.01§ 691 (20) <0.01§ 568 (21) <0.01§
Mean (SD) 11.1 (7.3) 7.6 (6.6) <0.01χ 7.7 (6.8) <0.01χ 7.5 (6.4) <0.01χ 7.6 (6.7) <0.01χ
Median (IQR) 10 (5-16) 6 (2-12)   5 (2-12)   6 (3-12)   6 (2-12)  
Systolic BP          
n (%) 301 (98) 7021 (84)   1853 (85)   2951 (85)   2217 (81)  
Mean (SD) 155 (29) 158 (31) 0.09§ 158 (31) 0.16§ 159 (31) 0.05§ 158 (30) 0.14§
Median (IQR) 152 (135-175) 155 (137-178) 0.10χ 155 (136-179) 0.13χ 157 (138-178) 0.03χ 154 (137-177) 0.54χ
Thrombolysis    0.10¥   0.08¥   0.08¥   0.17¥
Yes 5 (2) 294 (4)   128 (4)   128 (4)   85 (4)  
No 252 (98) 7008 (96)   2910 (96)   2910 (96)   2275 (96)  
  1. Abbreviations: SD standard deviation, IQR interquartile range, NIHSS National Institute of Health Stroke Score, OCSP Oxfordshire Community Stroke Project, LACS lacunar stroke, PACS partial anterior circulation stroke, TACS total anterior circulation stroke, POCS posterior circulation stroke, BP blood pressure.
  2. *October 2009.
  3. **December 2008 to April 2011 excluding October 2009.
  4. ***August-Novembers 2009, and 2010 excluding October 2009.
  5. The October 2009 data was excluded.
  6. Results reported as mean (standard deviation) and median (interquartile range) for continuous variables and number (%) for categorical data.
  7. §T-test for continuous data. Statistical difference performed on complete data only.
  8. ¥Pearson Chi2 test for categorical data. Statistical difference performed on complete data only.
  9. Fisher’s exact test for categorical data. Statistical difference performed on complete data only.
  10. χPearson Chi2 test for comparison of median. Statistical difference performed on complete data only.