|
Variables
|
Oct 2009 cohort (n = 308)
|
Full cohort (n = 8398)†
|
Autumn cohort (n = 2184)†
|
Winter cohort (n = 3478)†
|
Summer cohort (n = 2736)†
|
|---|
|
Results‡
|
p-value§vs. Oct 2009
|
Result‡
|
p-value§vs. Oct 2009
|
Result‡
|
p-value§vs. Oct 2009
|
Result‡
|
p-value§vs. Oct 2009
|
|---|
|
Age
| | | | | | | | | |
|
n (%)
|
258 (84)
|
8280 (99)
| |
2162 (99)
| |
3444 (99)
| |
2674 (98)
| |
|
Mean (SD)
|
78.3 (11.9)
|
76.3 (13.0)
|
0.01§
|
76.5 (12.7)
|
0.03§
|
76.5 (12.8)
|
0.02§
|
75.9 (n = 2674)
|
< 0.01§
|
|
Median (IQR)
|
80 (72-87)
|
79 (70-86)
|
0.19χ
|
79 (70-86)
|
0.36χ
|
79 (69-86)
|
0.20χ
|
79 (69-85)
|
0.11χ
|
|
Gender
| | |
0.06¥
| |
0.04¥
| |
0.05¥
| |
0.18¥
|
|
Female
|
172 (56)
|
4121 (51)
| |
1050 (50)
| |
1699 (50)
| |
1372 (52)
| |
|
Male
|
134 (44)
|
3998 (49)
| |
1057 (50)
| |
1682 (50)
| |
1259 (48)
| |
|
Pre-stroke residence
| | |
0.60¶
| |
0.31¶
| |
0.74¶
| |
0.47¶
|
|
Home
|
276 (92)
|
5231 (90)
| |
1533 (89)
| |
2115 (90)
| |
1583 (89)
| |
|
Care home
|
22 (7)
|
531 (9)
| |
169 (10)
| |
192 (8)
| |
170 (10)
| |
|
Other
|
3 (1)
|
69 (1)
| |
12 (1)
| |
37 (2)
| |
20 (1)
| |
|
Pre-stroke Rankin
| | |
0.07¶
| |
0.08¶
| |
0.05¶
| |
0.13¶
|
|
0
|
128 (50)
|
2501 (52)
| |
750 (51)
| |
981 (51)
| |
770 (53)
| |
|
1
|
54 (21)
|
813 (17)
| |
245 (17)
| |
342 (18)
| |
226 (15)
| |
|
2
|
20 (8)
|
572 (12)
| |
175 (12)
| |
236 (12)
| |
161 (11)
| |
|
3
|
28 (11)
|
545 (11)
| |
167 (11)
| |
210 (11)
| |
168 (11)
| |
|
4
|
23 (9)
|
322 (7)
| |
97 (7)
| |
112 (6)
| |
113 (8)
| |
|
5
|
2 (1)
|
103 (2)
| |
33 (2)
| |
42 (2)
| |
28 (2)
| |
|
Weekend
| | |
0.36¥
| |
0.59¥
| |
0.31¥
| |
0.32¥
|
|
Yes
|
84 (27)
|
2096 (25)
| |
564 (26)
| |
857 (25)
| |
675 (25)
| |
|
No
|
224 (73)
|
6302 (75)
| |
1620 (74)
| |
2621 (75)
| |
2061 (75)
| |
|
Time of admission
| | |
0.63¥
| |
0.73¥
| |
0.35¥
| |
0.99¥
|
|
0900 to 1700
|
164 (53)
|
4045 (48)
| |
1140 (52)
| |
1755 (50)
| |
1458 (53)
| |
|
1700 to 0900
|
144 (47)
|
4353 (52)
| |
1044 (48)
| |
1723 (50)
| |
1278 (47)
| |
|
Prior atrial fibrillation
| | |
0.10¥
| |
0.10¥
| |
0.16¥
| |
0.09¥
|
|
Yes
|
68 (35)
|
1123 (29)
| |
347 (29)
| |
407 (30)
| |
369 (29)
| |
|
No
|
127 (65)
|
2710 (71)
| |
850 (71)
| |
952 (70)
| |
908 (71)
| |
|
Type of stroke
| | |
0.23¥
| |
0.06¥
| |
0.36¥
| |
0.43¥
|
|
Ischaemic
|
260 (89)
|
6533 (87)
| |
1777 (85)
| |
2657 (87)
| |
2099 (88)
| |
|
Haemorrhagic
|
31 (11)
|
980 (13)
| |
307 (15)
| |
380 (13)
| |
293 (12)
| |
|
OCSP classification
| | |
0.01¥
| |
0.06¥
| |
0.01¥
| |
0.01¥
|
|
LACS
|
58 (23)
|
1195 (25)
| |
360 (25)
| |
480 (26)
| |
355 (24)
| |
|
PACS
|
116 (47)
|
1815 (38)
| |
566 (39)
| |
694 (38)
| |
555 (38)
| |
|
TACS
|
52 (21)
|
1012 (21)
| |
324 (22)
| |
373 (20)
| |
315 (21)
| |
|
POCS
|
22 (9)
|
711 (15)
| |
200 (14)
| |
277 (15)
| |
234 (16)
| |
|
NIHSS
| | | | | | | | | |
|
n (%)
|
46 (15)
|
1843 (22)
|
<0.01§
|
584 (27)
|
<0.01§
|
691 (20)
|
<0.01§
|
568 (21)
|
<0.01§
|
|
Mean (SD)
|
11.1 (7.3)
|
7.6 (6.6)
|
<0.01χ
|
7.7 (6.8)
|
<0.01χ
|
7.5 (6.4)
|
<0.01χ
|
7.6 (6.7)
|
<0.01χ
|
|
Median (IQR)
|
10 (5-16)
|
6 (2-12)
| |
5 (2-12)
| |
6 (3-12)
| |
6 (2-12)
| |
|
Systolic BP
| | | | | | | | | |
|
n (%)
|
301 (98)
|
7021 (84)
| |
1853 (85)
| |
2951 (85)
| |
2217 (81)
| |
|
Mean (SD)
|
155 (29)
|
158 (31)
|
0.09§
|
158 (31)
|
0.16§
|
159 (31)
|
0.05§
|
158 (30)
|
0.14§
|
|
Median (IQR)
|
152 (135-175)
|
155 (137-178)
|
0.10χ
|
155 (136-179)
|
0.13χ
|
157 (138-178)
|
0.03χ
|
154 (137-177)
|
0.54χ
|
|
Thrombolysis
| | |
0.10¥
| |
0.08¥
| |
0.08¥
| |
0.17¥
|
|
Yes
|
5 (2)
|
294 (4)
| |
128 (4)
| |
128 (4)
| |
85 (4)
| |
|
No
|
252 (98)
|
7008 (96)
| |
2910 (96)
| |
2910 (96)
| |
2275 (96)
| |
- Abbreviations: SD standard deviation, IQR interquartile range, NIHSS National Institute of Health Stroke Score, OCSP Oxfordshire Community Stroke Project, LACS lacunar stroke, PACS partial anterior circulation stroke, TACS total anterior circulation stroke, POCS posterior circulation stroke, BP blood pressure.
- *October 2009.
- **December 2008 to April 2011 excluding October 2009.
- ***August-Novembers 2009, and 2010 excluding October 2009.
- †The October 2009 data was excluded.
- ‡Results reported as mean (standard deviation) and median (interquartile range) for continuous variables and number (%) for categorical data.
- §T-test for continuous data. Statistical difference performed on complete data only.
- ¥Pearson Chi2 test for categorical data. Statistical difference performed on complete data only.
- ¶Fisher’s exact test for categorical data. Statistical difference performed on complete data only.
- χPearson Chi2 test for comparison of median. Statistical difference performed on complete data only.
