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Table 4 Pilot study - site actual accrual versus feasibility forecasts and research contract estimates

From: Accrual to a randomised trial of adjuvant whole brain radiotherapy for treatment of melanoma brain metastases is feasible

Site Code

State/country

How was the patient estimate was calculated

Number of patients estimated in the feasibility forecast

Number of patients estimated in the research contract

Was number of patients in research contract less than what was estimated in the Feasibility Forecast?

Actual patients accrued to study

Was accrual at the site within 50% of what was specified in the research contract?

1#

NOR

NA

10-15

5

Yes

15

Yes

2*

NSW

Records

5

5

No

20

Yes

3^

NSW

Memory

12

4

Yes

2

No

4*

NSW

Memory

5-6

6

No

0

No

5*

NSW

Memory

5-6

2

Yes

0

No

6^

NSW

Records

6

2

Yes

1

No

7*

NSW

Records

3

2

Yes

0

No

8*

NSW

Memory

8

4

Yes

1

No

9*

NSW

Memory

4

NS

NA

0

No

10*

VIC

Memory

20

10

Yes

2

No

11*

VIC

Records

10

5

Yes

1

No

12*

QLD

Records

2-3

2

Yes

3

Yes

13*

QLD

Memory

10

10

No

8

Yes

14*

QLD

Records

2-3

2

Yes

0

No

15*

QLD

Records

2

2

No

0

No

16*

SA

N/A

NA

2

NA

1

No

17*

WA

N/A

NA

NS

No

0

No

18^

VIC

N/A

10

NA

NA

NA

NA

19#

Europe

N/A

10

NA

NA

NA

NA

Total

  

124-133

63

10

54

4/17 Yes

  1. #Department of Medical Oncology.
  2. *Department of Radiation Oncology.
  3. ^Department of Neurosurgery.
  4. NOR – Norway; NSW – New South Wales; AU – Australia; VIC – Victoria; QLD – Queensland; SA – South Australia; WA – Western Australia; NA – not applicable; NS - Not specified.