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Table 2 Performance of lasso-based discrimination

From: Universal disease biomarker: can a fixed set of blood microRNAs diagnose multiple diseases?

Diseases

Accuracy

Sensitivity

Specificity

Optimals

AD

0.928

0.979

0.818

0.09

Carcinoma

0.818

0.867

0.760

0.9

CAD

0.884

0.769

1.000

0.24

NPC

0.900

0.935

0.842

1

HCC

0.825

0.650

1.000

0.03

BC

0.925

0.906

0.955

0.46

AML

0.985

1.000

0.923

0.64

Mean

0.895

0.872

0.900

 
  1. AD, Alzheimer’s disease; CAD, coronary artery disease; NPC, nasopharyngeal carcinoma; HCC, hepatocellular carcinoma; BC, breast cancer; AML, acute myeloid leukemia. s (fraction) is used for the predict.lars function (see Methods).