Table 3 Expression of e2f-1 and its correlation with clinicopathological parameters in 121 cases
From: Expressions and clinical significances of c-MET, p-MET and E2f-1 in human gastric carcinoma
Parameters | Grouping | n | e2f-1 [case (%)] | χ2test | ||
|---|---|---|---|---|---|---|
Positive | Negative | χ2value | P value | |||
Age (year) | <60 | 40 | 17(42.5) | 23(57.5) | 0.336 | 0.562 |
≥60 | 81 | 30(37.0) | 51(63.0) | |||
Gender | Male | 77 | 32(41.6) | 45(58.4) | 0.657 | 0.418 |
Female | 44 | 15(34.1) | 29(65.9) | |||
Tumor diameter (cm) | <5 | 48 | 27(56.3) | 21(43.7) | 10.148 | 0.001 |
≥5 | 73 | 20(23.4) | 53(76.6) | |||
Location of tumor | Cardia, fundus | 20 | 7(35.0) | 13(65.0) | 0.226 | 0.893 |
Body | 37 | 14(37.8) | 23(62.2) | |||
Pylorus, antrum | 64 | 26(60.6) | 38(59.4) | |||
Lauren classification | Intestinal | 84 | 36(42.9) | 48(57.1) | 1.863 | 0.172 |
Diffuse | 37 | 11(29.7) | 26(70.3) | |||
Histological type | Grade 1 | 25 | 10(40.0) | 15(60.0) | 0.236 | 0.889 |
Grade 2 | 47 | 17(36.2) | 30(63.8) | |||
Grade 3 | 49 | 20(40.8) | 29(59.2) | |||
Invasion depth | T1 | 18 | 12(66.7) | 6(33.3) | 14.143 | 0.003 |
T2 | 32 | 17(53.1) | 15(46.9) | |||
T3 | 30 | 7(23.3) | 23(76.7) | |||
T4 | 41 | 11(26.8) | 30(73.2) | |||
Metastatic lymph node ratio | <35% | 60 | 30(50.0) | 30(50.0) | 6.237 | 0.013 |
≥35% | 61 | 17(27.9) | 44(72.1) | |||
Involving lymph node station | N0 | 43 | 21(48.8) | 22(51.2) | 6.739 | 0.081 |
N1 | 41 | 17(41.5) | 24(58.5) | |||
N2 | 26 | 8(30.8) | 18(69.2) | |||
N3 | 11 | 1(9.1) | 10(90.91) | |||
TNM stages | Ia | 16 | 10(62.5) | 6(37.5) | 13.724 | 0.017 |
Ib | 17 | 8(47.1) | 9(52.9) | |||
II | 20 | 11(55.0) | 9(45.0) | |||
IIIa | 20 | 8(40.0) | 12(60.0) | |||
IIIb | 22 | 6(27.3) | 16(72.7) | |||
IV | 26 | 7(26.9) | 19(73.1) | |||
Survival (month) | <20 | 75 | 52(69.3) | 23(30.7) | 10.356 | 0.005 |
≥20 | 46 | 20/(43.5) | 26/(56.5) | |||