Table 2 The performance of various SVM models was developed using AC, DC, PSSM profiles and Hybrid methods on the individual Pg-activators SAK, SK, UK and tPA in five-fold cross validation
Proteins | Methods | ACC(%) | SN(%) | SP(%) | MCC | Parameters | |
|---|---|---|---|---|---|---|---|
|  |  |  |  |  |  | γ | C |
SAK | AC | 96.06 | 92.30 | 96.91 | 0.93 | 3 | 300 |
DC | 86.82 | 87.08 | 86.76 | 0.83 | 3 | 75 | |
PSSM | 93.98 | 92.28 | 94.34 | 0.92 | 1 | 300 | |
Hybrid | 91.72 | 96.63 | 90.62 | 0.93 | 1 | 150 | |
SK | AC | 95.77 | 99.05 | 92.92 | 0.95 | 3 | 275 |
DC | 86.40 | 93.12 | 80.56 | 0.82 | 10 | 25 | |
PSSM | 97.10 | 100 | 94.44 | 0.97 | 1 | 400 | |
Hybrid | 90.75 | 99.05 | 83.55 | 0.90 | 1 | 250 | |
tPA | AC | 95.83 | 100 | 95.71 | 0.97 | 50 | 100 |
DC | 92.70 | 70.58 | 93.35 | 0.78 | 15 | 450 | |
PSSM | 97.73 | 100 | 97.67 | 0.98 | 4 | 200 | |
Hybrid | 92.69 | 75.00 | 93.20 | 0.81 | 10 | 450 | |
UK | AC | 90.68 | 100 | 86.77 | 0.93 | 3 | 300 |
DC | 87.03 | 95.03 | 83.66 | 0.87 | 15 | 500 | |
PSSM | 92.06 | 93.19 | 91.56 | 0.90 | 5 | 9 | |
Hybrid | 85.03 | 99.40 | 79.00 | 0.88 | 1 | 450 | |