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Table 1 miRNAs differentially expressed in rat liver after PH and comparison with miRNA expression after SL

From: Independent effects of sham laparotomy and anesthesia on hepatic microRNA expression in rats

miRNA FC (SL/control) FC (PH/control) Accession No.
 12 h  24 h  48 h  12 h  24 h  48 h
A miRNAs similarly deregulated after partial hepatectomy and sham laparotomy
rno-miR-100 0.72* 0.92 0.86 0.69** 0.70** 0.88 MIMAT0000822
rno-miR-105 1.56* 1.50*** 1.49 ** 1.49 1.50*** 1.61* MIMAT0012825
rno-miR-133a 0.99 0.76* 0.70* 0.75 0.68** 0.80 MIMAT0000839
rno-miR-133b 0.82 0.68* 0.74 0.88 0.59** 0.84 MIMAT0003126
rno-miR-383 1.16 1.26* 1.25 1.25 1.29* 1.07 MIMAT0003114
rno-miR-466c 1.24 1.33** 1.03 1.36 1.53*** 1.28 MIMAT0005279
rno-miR-483 0.78* 0.82*** 0.73*** 0.60*** 0.70*** 0.56*** MIMAT0003121
rno-miR-598-5p 1.32 1.41** 1.32 1.46 1.40* 1.24 MIMAT0005324
rno-miR-628 1.29 1.37* 1.22 1.38* 1.31* 1.24 MIMAT0012836
rno-miR-1224 0.72 0.73*** 0.79 0.65* 0.69** 0.64* MIMAT0012827
B miRNAs with opposite regulation after partial hepatectomy and sham laparotomy
rno-miR-29a 1.05 1.24** 1.17 0.91 0.78*** 0.85 MIMAT0000802
C miRNAs with deregulation after sham laparotomy but not following partial hepatectomy
rno-miR-23b 0.97 1.21*** 1.16* 0.87 0.80* 0.86 MIMAT0000793
rno-miR-30b-5p 1.14 1.22** 1.17 0.88 0.88* 0.90 MIMAT0000806
rno-miR-31 1.16 1.21*** 1.24* 0.95 0.92 0.85 MIMAT0000810
rno-miR-92b 0.70* 0.75** 0.66*** 0.87 0.92 0.89 MIMAT0005340
rno-miR-129 0.81 0.86 0.77* 1.03 0.86 0.87 MIMAT0000600
rno-miR-143 1.27 1.32*** 1.38* 1.06 0.98 1.00 MIMAT0000849
rno-miR-151 1.13 1.21** 1.18* 0.91 0.93 0.91 MIMAT0000614
rno-miR-191 1.12 1.27*** 1.22* 0.98 0.96 1.04 MIMAT0000866
rno-miR-192 1.15 1.21** 1.18 0.94 0.87** 0.95 MIMAT0000867
rno-miR-194 1.17 1.22** 1.20 0.93 0.88** 0.96 MIMAT0000869
rno-miR-195 1.18 1.21*** 1.17* 0.95 0.87 0.92 MIMAT0000870
rno-miR-201 1.33* 1.30** 1.30* 1.31 1.18 1.11 MIMAT0012846
rno-miR-205 0.75 0.68** 0.76* 0.94 0.97 0.92 MIMAT0000878
rno-miR-224 1.12 1.28 1.46* 1.06 1.14 1.40 MIMAT0003119
rno-miR-295 0.82 0.67** 0.69* 0.99 0.91 0.89 MIMAT0012849
rno-miR-296 0.78 0.77* 0.76 0.84 0.86 0.89 MIMAT0004742
rno-miR-324-5p 0.77 0.76** 0.77* 0.91 0.89 0.92 MIMAT0000553
rno-miR-331 0.76 0.81 0.70* 0.79 0.71* 0.87 MIMAT0000570
rno-miR-337 1.12 1.42** 1.34 1.14 1.23 1.45 MIMAT0000577
rno-miR-343 0.70* 0.73* 0.68* 0.78 0.81 0.85 MIMAT0000591
rno-miR-365 0.66* 0.83* 0.76* 0.85 0.87 0.80 MIMAT0001549
rno-miR-425 1.14 1.21* 1.27* 1.14 1.05 1.12 MIMAT0005314
rno-miR-429 0.91 0.74** 0.81 0.95 0.91 0.81 MIMAT0001538
rno-miR-484 0.75* 0.66*** 0.61*** 0.89 0.81* 0.71 MIMAT0005319
rno-miR-511 0.94 1.32 1.47* 0.98 0.99 1.12 MIMAT0012829
rno-miR-532-5p 0.99 1.22* 1.22 1.05 0.98 1.05 MIMAT0005322
rno-miR-615 0.78 0.71* 0.87 0.93 0.92 0.96 MIMAT0012835
rno-miR-664 0.88 0.83 0.74* 0.81 0.73* 0.89 MIMAT0003382
rno-miR-667 0.81 0.85** 0.79** 0.84 0.83 0.84 MIMAT0012852
rno-miR-668 0.80 0.73** 0.85 0.94 0.90 0.87 MIMAT0012839
rno-miR-708 1.55* 1.37* 1.47* 1.25 1.21 1.18 MIMAT0005331
rno-miR-760-3p 0.67* 0.81 0.81 1.08 1.05 0.87 MIMAT0005337
rno-miR-760-5p 0.78* 0.73*** 0.74** 0.89 0.84 0.88 MIMAT0005336
rno-miR-880 0.91 0.74* 0.94 0.87 0.81 0.78 MIMAT0005288
  1. miRNAs listed in this table were significantly deregulated at the same time point after sham laparotomy or after partial hepatectomy in rat liver tissue (<0.8 fold change or > 1.2 fold change compared to normal rat tissue; Empirical Bayes Statistics adjusted for multiple testing, each time point compared with 0 h; *p < 0.05, **p < 0.01, ***p < 0.001). Boldface indicates miRNA deregulation at the same postoperative time point. Abbreviations: FC fold change, SL sham laparotomy, PH partial hepatectomy.