|
Parameter
|
Group
|
Baseline
|
60 min
|
120 min
|
180 min
|
240 min
|
|---|
|
Natrium
|
C-group
|
139.4 (1.4)
|
139.1 (1.5)
|
139.1 (2.4)
|
139.1 (2.4)
|
138.2 (1.4)**
|
|
(mmol/l)
|
P-group
|
139.0 (1.5)
|
138.9 (1.8)
|
138.4 (2.3)
|
138.0 (3.2)
|
138.0 (2.1)
|
|
Kalium
|
C-group
|
4.2 (0.2)
|
4.4 (0.3)*
|
4.6 (0.3)**
|
4.9 (0.3)***
|
5.3 (0.5)***
|
|
(mmol/l)
|
P-group
|
4.3 (0.5)
|
4.5 (0.5)*
|
5.0 (0.7)**
|
5.9 (1.2)*
|
6.1 (0.9)***
|
|
Chloride
|
C-group
|
99.1 (1.4)
|
98.6 (0.9)
|
98.6 (0.9)
|
99.4 (1.1)
|
98.6 (1.1)
|
|
(mmol/l)
|
P-group
|
99.2 (1.3)
|
98.5 (1.2)
|
98.6 (2.3)
|
98.1 (2.0)
|
98.9 (1.7)
|
|
Osmolalitet
|
C-group
|
285.8 (2.4)
|
288.4 (6,6)
|
283.8 (1.8)
|
282.8 (3.6)
|
284.5 (4.9)
|
|
(mosm/l)
|
P-group
|
282.4 (4.6)
|
281.9 (2.7)
|
283.1 (3.6)
|
284.3 (3.2)
|
285.9 (4.7)
|
|
s-Protein
|
C-group
|
47.0 (2.1)
|
46.4 (2.1)
|
44.5 (2.1)**
|
43.4 (1.8)***
|
43.3 (1.2)**
|
|
(g/l)
|
P-group
|
46.9 (3.1)
|
49.3 (3.4)*
|
47.9 (3.2)
|
47.9 (4.4)
|
47.8 (3.6)#
|
|
s-Albumin
|
C-group
|
31.1 (4.3)
|
30.9 (4.0)
|
29.5 (4.3)**
|
29.8 (3.7)
|
28.9 (3.4)*
|
|
(g/l)
|
P-group
|
31.4 (2.9)
|
32.6 (3.0)
|
31.9 (2.4)
|
32.3 (2.4)
|
32.3 (2.7)
|
|
Albuminmass
|
C-group
|
2,02 (0.42)
|
1.98 (0.39)
|
1.89 (0.37)*
|
1.93 (0.37)
|
1.87 (0.41)**
|
|
(g/kg)
|
P-group
|
1.86 (0.21)
|
1.76 (0.22)**
|
1,71 (0.21)***
|
1.52 (0.21)***
|
1.45 (0.19)***
|
|
Proteinmass
|
C-group
|
3.03 (0.3)
|
2.97 (0.31)
|
2.84 (0.28)*
|
2.8 (0.25)*
|
2.78 (0.32)*
|
|
(g/kg)
|
P-group
|
2.79 (0.41)
|
2.67 (0.43)**
|
2.59 (0.41)***
|
2.28 (0.43)***
|
2.16 (0.33)#***
|
|
Hemoglobin
|
C-group
|
8.0 (0.6)
|
7.8 (0.6)##
|
7.9 (0.8)#
|
7.9 (0.9)###
|
7.7 (0.8) ###
|
|
(g/100 ml)
|
P-group
|
8.6 (0.6)
|
9.1 (0.6)**
|
9.2 (0.8)**
|
9.9 (0.6)***
|
10.1 (0.7)***
|
|
pH
|
C-group
|
7.50 (0.04)
|
7.50 (0.03)
|
7.51 (0.04)
|
7.50 (0.03)
|
7.51 (0.02)##
|
| |
P-group
|
7.52 (0.05)
|
7.50 (0.04)
|
7.49 (0.04)
|
7.45 (0.06)
|
7.43 (0.05)*
|
|
BE
|
C-group
|
7.74 (1.5)
|
8.08 (1.5)
|
8.31 (1.2)
|
8.49 (1.1)##
|
7.81 (1.1)##
|
|
(mmol/l)
|
P-group
|
7.65 (1.1)
|
7.36 (1.1)
|
6.85 (1.0)
|
5.68 (1.5)
|
5.29 (1.2)*
|
|
P
a
CO
2
|
C-group
|
5.3 (0.5)
|
5.5 (0.4)
|
5.3 (0.5)
|
5.5 (0.5)
|
5.2 (0.5)#
|
|
(kPa)
|
P-group
|
5.1 (0.7)
|
5.3 (0.6)
|
5.4 (0.4)
|
5.8 (0.9)
|
6.2 (0.7)
|
|
HCO
3
-
|
C-group
|
31.5 (1.4)
|
31.8 (1.4)
|
32.1 (1.1)
|
32.2 (1.0)#
|
31.6 (0.9)##
|
|
(mmol/l)
|
P-group
|
31.4 (0.9)
|
31.2 (1.1)
|
30.7 (1.0)
|
29.7 (1.7)
|
29.1 1.3)*
|
|
P
a
O
2
|
C-group
|
34.4 (11.9)
|
28.1 (5.4)
|
26.9 (4.0)
|
26.0 (4.8)
|
26.2 (5.6)
|
|
(kPa)
|
P-group
|
25.8 (4.9)
|
24.7 (4.0)
|
24.1 (5.5)
|
24.8 (4.5)
|
22.7 (5.3)
|
|
TNF-α
|
C-group
|
72.0 (28.9)
|
79.5 (27.3)
|
83.0 (27.0)
|
77.1 (24.1)
|
80.7 (29.0)
|
|
(pg/ml)
|
P-group
|
56.8 (21.1)
|
63.2(19.4)
|
64.7 (22.1)
|
87.8 (29.6)**
|
91.4 (38.4)*
|
|
Interleukin-6
|
C-group
|
3.6 (4.7)
|
9.0 (3.4)**
|
17.6 (3.4)***
|
23.9 (8.0)***
|
30.2 (14.5)**
|
|
(pg/ml)
|
P-group
|
10.5 (7.8)
|
16.5 (11.8)**
|
30.9 (13.1)***
|
52.8 (26.2)***
|
83.0 (64.4)
|
-
Results as means with SD in parentheses; Control group: C-group; Intervention group: P-group; *:P<0.05 **:P<0.01 ***:P<0.001; within group differences compared with baseline values; #:P<0.05 ##:P<0.01 ###:P<0.001; between group differences, same time.
