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Table 3 Efficiency tests of Guidance and DivA

From: DivA: detection of non-homologous and very divergent regions in protein sequence alignments

 

TPR

FDR

PPV

  

Method

200 only birds

200 all species

200 only birds

200 all species

200 only birds

200 all species

Guidance Score <=0.4

0.3687836

0.3687836

0.9084643

0.9084643

0.09153575

0.09153575

Guidance Score <=0.8

0.5439066

0.7788185

0.928089

0.8882818

0.07191096

0.1117182

DivA

0. 810281

0. 469429

0. 3775697

0. 5588211

0. 6224303

0. 4411789

  1. Guidance performance on the datasets of 200 only-birds alignments and the 200 alignments with very divergent species included was compared to DivA. Two threshold values, 0.4 and 0.8, were used in Guidance to consider a sequence region as potentially non-homologous.