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Table 2 Risk of low FGLP-1, 1hGLP-1, and ∆GLP-1 levels for T2DM

From: The low level of glucagon-like peptide-1 (glp-1) is a risk factor of type 2 diabetes mellitus

 

T2DM

NGT

OR (95% CI)

P

Fasting state

Low FGLP-1 (<2.21 pg/L)

12 (60%)

2 (10%)

13,5 (2.434-74.867)

0.001

Normal GLP-1 (≥2.21 pg/L)

8 (40%)

18 (90%)

Post-glucose loading state

Low 1hGLP-1 (<2.57 pg/L)

10 (50%)

3 (15%)

5.667 (1.254-25.606)

0.018

Normal 1hGLP-1 (≥2.57 pg/L)

10 (50%)

17 (85%)

Difference ()

Low ∆GLP-1 (<0.029 pg/L)

2 (10%)

2 (10%)

1.00 (0.127-7.893)

1.0

Normal ∆GLP-1 (≥0.029 pg/L)

18 (90%)

18 (90%)

  
  1. T2DM, type 2 diabetes mellitus; NGT, normal glucose tolerance; FGLP-1, fasting GLP-1; 1hGLP-1, 1 h after glucose loading GLP-1; DGLP-1, responses of GLP-1 after loading.