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Table 2 The genotypes and allele distribution of hTERT variants in breast cancer patients and the control group

From: Association between hTERT polymorphisms and the risk of breast cancer in a sample of Southeast Iranian population

Variants Patients n (%) Controls n (%) OR (95% CI) p
MNS16A Genotype     
 L/L 115 (43.2) 66 (29.5) 1.00 -
 L/S 136(51.1) 153(68.3) 0.51 (0.35-0.75) <0.001
 S/S 15 (5.7) 5 (2.2) 1.72 (0.61-4.95) 0.460
 L/S + S/S 151 (56.8) 158 (65.5) 0.55 (0.38-0.81) 0.002
Allele     
 L 366 (68.8) 285 (63.6) 1.00 -
 S 166 (31.2) 163 (36.7) 0.79 (0.61-1.03) 0.090
rs2736098     
 AA 40 (15.8) 58 (26.1) 1.00 -
 AG 140 (55.3) 113 (50.9) 1.80 (1.12-2.88) 0.017
 GG 72 (28.5) 51 (23.0) 1.80 (1.06-3.06) 0.033
 AG + GG 212 (83.8) 164 (73.9) 1.87 (1.19-2.94) 0.006
Allele     
 A 220 (43.7) 229 (51.6) 1.00 -
 G 284 (56.3) 215 (48.4) 1.38 (1.06-1.78) 0.016
rs2735940     
 CC 45 (17.0) 39 (17.3) 1.00 -
 CT 124 (47.0) 138 (61.3) 0.78 (0.48-1.28) 0.380
 TT 95 (36.0) 48 (21.3) 1.72 (0.99-2.98 0.066
 CT + TT 219 (83.0) 186 (82.6) 1.02 (0.64-1.64) 0.991
Allele     
 C 214 (40.5) 216 (48.0) 1.00 -
 T 314 (59.5) 234 (52.0) 1.35 (1.05-1.75) 0.020