Skip to main content

Advertisement

Table 2 Comparison between clinical features, investigation findings and outcome of HSV encephalitis in the general population and those pregnant

From: Herpes simplex virus encephalitis in pregnancy - a case report and review of reported patients in the literature

  Pregnant patients with HSV encephalitis General population with HSV-1 encephalitis [ 4 ] p value General population with HSV encephalitis [ 5 ] p value
Fever 89% (16/18) 76% (29/38) 0.75 92% (90/98) 0.22
Headache 67% (12/18) 42% (16/38) 0.1 NK NK
Seizures 45% (8/18) 63% (24/38) 0.17 32% (31/98) 0.32
Mean GCS on admission (where documented) 14.6 NK NK 13.7 NK
Coma on admission (GCS < 8, where GCS documented) 0% (0/8) 24% (9/38) 0.32 9% (9/98) 0.36
Abnormal CT 40% (4/10) 56% (18/32) 1.0 79% (72/91) 0.17
(if performed)      
Abnormal MRI 80% (8/10) 89% (25/28) 0.59 NK NK
(if performed)      
Abnormal EEG 92% (11/12) 81% (22/27) 0.64 NK NK
(if performed)      
WCC mean (range) 177 (0–623) 46 (10–1278) 0.51 237 (1–3900) NK
Death 3/18 (17%) 11% (4/38) 0.67 13/85 (15%) 1.0
  1. Footnote: Population 4: Granerod et al [4]; Population 5: Raschilas et al [5].