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Table 1 Clinical and functional measures before and during therapy with vemurafenib

From: Excellent response of intramedullary Erdheim-Chester disease to vemurafenib: a case report

Measure

Baseline

1 month

3 months

Tumor size (mm2)

142

65

58.8

Spasticity knee (Ashworth scale)

2

2

1

Spasticity ankle (Ashworth scale)

1

1

0

Walking aids

two crutches

variable

none

Gait test*

300

370 m

405 m

Legg press

30 kg

not done

70 kg

Treadmill

1 km

1-2 km

3 km

  1. Tumor size is given in area of the largest cross section through the tumor.
  2. *Maximal distance at fast walking pace during 6 minutes.