Skip to main content

Table 3 Summary of biological processes enriched when all three PMT are combined (p < 0.01, FWFDR < 0.10)

From: Transcriptional profiling of PRKG2-null growth plate identifies putative down-stream targets of PRKG2

GO Term

# genes

% total

P-value

Benjamini *

GO:0048522 ~ positive regulation of cellular process

136

8.50%

1.85E-07

7.82E-05

GO:0048518 ~ positive regulation of biological process

149

9.31%

1.01E-07

8.51E-05

GO:0048519 ~ negative regulation of biological process

154

9.62%

4.53E-07

1.28E-04

GO:0048523 ~ negative regulation of cellular process

148

9.25%

6.73E-07

1.42E-04

GO:0006996 ~ organelle organization and biogenesis

152

9.50%

2.39E-06

4.03E-04

GO:0048731 ~ system development

207

12.94%

6.89E-06

9.69E-04

GO:0030154 ~ cell differentiation

210

13.12%

3.55E-05

4.27E-03

GO:0008219 ~ cell death

108

6.75%

4.13E-05

4.35E-03

GO:0009892 ~ negative regulation of metabolic process

64

4.00%

6.11E-05

5.71E-03

GO:0051726 ~ regulation of cell cycle

74

4.62%

7.60E-05

6.39E-03

GO:0044260 ~ cellular macromolecule metabolic process

369

23.06%

9.27E-05

7.09E-03

GO:0009893 ~ positive regulation of metabolic process

64

4.00%

1.12E-04

7.85E-03

GO:0019538 ~ protein metabolic process

381

23.81%

1.83E-04

0.012

GO:0022402 ~ cell cycle process

94

5.88%

4.13E-04

0.025

GO:0007626 ~ locomotory behavior

33

2.06%

5.76E-04

0.030

GO:0042127 ~ regulation of cell proliferation

67

4.19%

5.46E-04

0.030

GO:0044248 ~ cellular catabolic process

77

4.81%

6.41E-04

0.031

GO:0006397 ~ mRNA processing

40

2.50%

7.12E-04

0.033

GO:0048513 ~ organ development

146

9.12%

8.33E-04

0.036

GO:0050790 ~ regulation of catalytic activity

64

4.00%

1.33E-03

0.050

GO:0006928 ~ cell motility

57

3.56%

1.22E-03

0.050

GO:0043067 ~ regulation of programmed cell death

70

4.38%

1.30E-03

0.051

GO:0009653 ~ anatomical structure morphogenesis

129

8.06%

1.77E-03

0.063

GO:0008380 ~ RNA splicing

34

2.12%

2.95E-03

0.095

GO:0003012 ~ muscle system process

27

1.69%

3.08E-03

0.095

GO:0051641 ~ cellular localization

105

6.56%

2.85E-03

0.096

GO:0051649 ~ establishment of cellular localization

102

6.38%

3.37E-03

0.097

GO:0006730 ~ one-carbon compound metabolic process

18

1.12%

3.28E-03

0.098

  1. *Benjamini is a measure of family-wise false discovery rate as described by Huang da et al. [13].