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Table 2 IC50 values (nM) of cetuximab treatment in three HNSCC cell lines (mean ± standard deviation)

From: The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines

Cell line

Normoxia

24 h hypoxia

72 h hypoxia

LICR-HN2

0.08 ± 0.03

0.12 ± 0.05

0.08 ± 0.08

LICR-HN5

0.42 ± 0.10

0.37 ± 0.09

1.17 ± 0.47

SC263

2.38 ± 0.59

0.64 ± 0.38

0.10 ± 0.05