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Figure 2 | BMC Research Notes

Figure 2

From: Distal 10q trisomy with copy number gain in chromosome region 10q23.1–10q25.1: the Wnt signaling pathway is the most pertinent to the gene content in the region of copy number gain: a case report

Figure 2

Array-comparative genomic hybridization and validation by quantitative real-time polymerase chain reaction analysis. a Array-comparative genomic hybridization analysis of patient genomic DNA vs. normal male genomic DNA. The characteristic duplication in the 10q23.1–10q25.1 region is clearly detectable in both the chromosomal segmentation analysis (upper panel) and the chromosome 10 profile (bottom panel). b The result of quantitative real-time polymerase chain reaction validation indicates that 23 successive representative target sequences representing the DNA sequence of Ch10:86591156–108394653 were confirmed in the triplicate copy number variation status (relative copy number ≥1.5).

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BMC Research Notes

ISSN: 1756-0500

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