Pancreatic cancer-associated gene polymorphisms in a nation-wide cohort of p16-Leiden germline mutation carriers; a case–control study

Table 2 Association of seven selected SNPs with pancreatic cancer in this study

Marker^a	Minor Allele Frequency		Allelic OR (95% CI)	Sign. (p value)
Marker^a	Cases	Controls	Allelic OR (95% CI)	Sign. (p value)
rs2821367 (T, C) 1q32.1 NR5A2	0.37	0.38	1.0 (0.62–1.62)	1.00
rs7310409 (G, A) 12q24.31 HNF1A	0.35	0.39	0.87 (0.54–1.41)	0.57
rs735396 (A, G) 12q23.31 HNF1A	0.33	0.36	0.90 (0.55–1.47)	0.67
rs1805100 (G, A) 8q21.11 HNF4G	0.49	0.56	0.76 (0.48–1.21)	0.24
rs505922 (T, C) 9q34.2 ABO	0.30	0.33	0.87 (0.53–1.44)	0.59
rs657152 (G, T) 9q34.2 ABO	0.30	0.37	0.73 (0.44–1.20)	0.22
rs172310 (C, A) 7q36.3 SHH	0.43	0.39	1.18 (0.74–1.89)	0.49

ISSN: 1756-0500