Skip to main content

Table 3 Comparison of clinical characteristics between CD alone vs. with CD and EoE

From: Eosinophilic esophagitis associated with celiac disease in children

Clinical characteristics CD (n = 50) mean ± SD or n (%) CD and EoE (n = 6) mean ± SD or n (%) P value
Demographics
 Age at diagnosis (years) 10.5 ± 4.3 11.6 ± 1.6 0.536
 Gender
  Male/Female 17 (34)/33 (66) 5 (83)/1 (17) 0.030
 Race
  Caucasian/Other 48 (96)/2 (4) 5 (83)/1 (17) 0.293
  Duration of symptoms (months) 13.8 ± 14.6 15.9 ± 12.2 0.738
 History of allergies
  Asthma 2 (4) 1 (17) 0.293
  Food allergy 8 (16) 4 (67) 0.016
 Presenting symptoms
  Abdominal pain 27 (54) 4 (67) 0.682
  Dysphagia 0 (0) 1 (17) 0.107
  Failure to thrive 12 (24) 3 (50) 0.326
  Diarrhea/Constipation 18 (36) 0 (0) 0.162
 Endoscopy findings
  Normal esophagus 50 (100) 0 (0) <0.0005
  Ringed esophagus 0 (0) 1 (17) 0.035
  Esophageal mucosal furrows 0 (0) 5 (85) 0.0005
  White plaques in esophagus 0 (0) 4 (67) 0.001
  Normal duodenum 24 (48) 4 (67) 0.669
  Scalloping duodenum 25 (50) 2 (33) 0.671
 Histopathological findings
  TTG IgA (U/mL) 164.4 ± 129.2 248.7 ± 82.4 0.058
  Esophageal eosinophilia 1.1 ± 2.4 42 ± 20 0.0001
 Marsh score
  1 8 (16) 0 (0)
  2 8 (16) 2 (33)
  3a 16 (32) 0 (0)
  3b 18 (36) 4 (67)
  1. CD celiac disease, EoE eosinophilic esophagitis, TTG IgA anti-tissue transglutaminase antibody IgA, SD standard deviation.