Fig. 2
From: Challenges in exome analysis by LifeScope and its alternative computational pipelines
Coverage of target regions by mapping methods. Average coverage of the targeted exome regions by the mapped reads in family exomes is shown. Five coverage intervals that we created to assess mappings of different methods are presented in the legend. They comprise intervals of [1,10), [10,20), [20,30), [30,60), [60,100) and equal and higher than 100. Each individual barplot shows a percentages of the targeted regions falling into a coverage category for each mapping method: LifeScope, SHRiMP, MAQ and BFAST. The targeted regions are mostly covered by 30–60 reads in all mapping methods