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Table 5 Mean area under curve of Chi8 and GBOOST on simulated GWAS of 1600 subjects

From: Chi8: a GPU program for detecting significant interacting SNPs with the Chi-square 8-df test

Allele freq.

0.1

0.2

0.4

Model 1

 Chi8

0.56

0.15

0.04

 GBOOST

0.43

0.54

0.22

Model 2

 Chi8

0.46

0.98

0.97

 GBOOST

0.49

0.98

0.98

Model 3

 Chi8

0.68

0.65

0.93

 GBOOST

0.37

0.62

0.97

Model 4

 Chi8

0.35

0.89

1

 GBOOST

0.43

0.98

0.98

  1. To account for Chi8’s sensitivity to univariate significant SNPs we only consider reported pairs where both SNPs are also individually insignificant
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BMC Research Notes

ISSN: 1756-0500

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