Fig. 1

Well-being in patients with immunodeficiency disorders before and after 1 year of supplementation with vitamin D. In patients with a better well-being during the study (n = 72) there was an average increase in 25-hydroxyvitamin D levels (25-OHvitD) (p < 0.001, Student’s t-test). Likewise, in patients with no difference in well being (n = 32) there was an average increase, but less pronounced (p < 0.05, Student’s t-test). In patients stating a worse well-being (n = 14) there was no significant increase (ns not significant)