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Table 2 Bivariate analysis for genital symptoms and infections among cases (had PROM) and controls (without PROM)

From: Genital infections and risk of premature rupture of membranes in Mulago Hospital, Uganda: a case control study

Variable Cases
N = 87 (100 %)
Controls
N = 87 (100 %)
P value OR (95 % CI)
Abnormal vaginal discharge
 Yes 47 (54.0) 32 (36.8) 0.023 2.02 (1.10–3.70)
 No 40 (46.0) 55 (63.2)   
Painful genital ulcer history
 Yes 9 (10.3) 3 (3.4) 0.087 3.23 (0.84–12.37)
 No 78 (89.7) 84 (56.6)   
HSV-2 serology
 Positive 49 (56.0) 46 (53.0) 0.648 1.15 (0.63–2.09)
 Negative 38 (44.0) 41 (56.6)   
HSV-2 ELISA optical densities
 >3.4 (high positives) 32 (37.0) 19 (22.0) 0.032 2.08 (1.07–4.07)
 ≤3.4 (negative or low positive) 55 (63.0) 68 (78.0)   
HIV status
 Positive 12 (13.8) 12 (13.8) 0.098 0.99 (0.42–2.34)
 Negative 75 (86.2) 75 (86.2)   
Candida
 Positive 18 (20.7) 43 (49.4) <0.001 0.27 (0.14–0.52)
 Negative 69 (79.3) 44 (50.6)   
Trichomonas vaginalis
 Positive 18 (20.7) 7 (8.0) 0.02 2.98 (1.18–7.56)
 Negative 69 (79.3) 80 (92.0)   
Bacterial vaginosis     
 Positive 0 (0.0) 2 (2.3) a  
 Negative 87 (100.0) 85 (97.7)   
Neisseria gonococcus
 Positive 0 (0.0) 1 (1.1) a  
 Negative 87 (100.0) 86 (98.9)   
Chlamydia trachomatis
 Positive 4 (4.6) 2 (2.3) 0.415 2.05 (0.37–11.49)
 Negative 83 (95.4) 85 (97.7)   
Syphilis
 Positive 0 (0.0) 0 (0.0) a  
 Negative 100 (100.0) 100 (100.0)   
  1. We assessed the association between PROM and: abnormal vaginal discharge, history of painful genital ulcer, candidiasis, Trichomonas vaginalis, preterm labour, HSV-2 serostatus, HSV-2 titres, HIV, bacterial vaginosis, Neisseria gonorrhoea, Group B streptococcus and with syphilis. The italicized odds ratios had a significant association with PROM (abnormal vaginal discharge, candidiasis, Trichomonas vaginalis, and preterm labour and HSV-2 titres)
  2. aMeans no further analysis was done for these variables due to few numbers