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Table 3 Antibiotic susceptibility of blood culture isolates from cancer patients at KBTH

From: Bloodstream infections in patients with malignancies: implications for antibiotic treatment in a Ghanaian tertiary setting

Microorganisms Resistance to antimicrobial agents (%)
AMP CRX AUG GEN AMK CIP LEV COT TET CTX CHL
Gram negatives (n = 49) a33/33 (100.0) a28/36 (77.7) a4/5 (80.0) a15/39 (39.5) 13/38 (34.2) 7/18 (38.8) 4/17 (23.5) a30/33 (90.9) a28/30 (93.3) 25/41 (60.9) 25/29 (86.2)
 Enterobacteriaceae (n = 32) 28/28 (100.0) 23/29 (79.3) 3/4 (75.0) 9/24 (42.8) 9/31 (29.0) 7/11 (63.6) 2/8 (40.0) 25/28 (89.9) 24/25 (96.0) 20/32 (62.5) 20/23 (86.9)
  Escherichia coli (n = 8) 7/7 (100.0) 4/5 (80.0) 1/1 (100) 3/8 (37.5) 4/7 (57.1) 4/5 (80.0) 0/2 (0.0) 6/6 (100) 5/6 (83.3) 4/8 (50.0) 6/6 (100)
  K. pneumoniae (n = 3) 3/3 (100.0) 2/3 (66.7) 2/3 (66.7) 0/3 (0.0) 1/1 (100) 0/1 (0.0) 3/3 (100) 3/3 (100) 3/3 (100) 3/3 (100)
  Citrobacter species (n = 12) 9/9 (100.0) 9/12 (75.0) 0/1 (0.0) 4/12 (33.3) 3/12 (25.0) 0/1 (0.0) 1/3 (33.3) 8/11 (72.7) 10/10 (100) 7/12 (63.6) 7/10 (70.0)
  Enterobacter species (n = 7) 7/7 (100.0) 7/7 (100.0) 2/2 (100.0) 2/7 (28.7) 2/4 (50.0) 1/2 (50.0) 6/6 (100) 5/5 (100) 6/7 (85.7) 4/4 (100)
  Providencia species (n = 1) 1/1 (100) 0/1 (0.0) 0/1 (0.0) 0/1 (0.0) 1/1 (100) 0/1 (0.0)
  Salmonella typhimurium (n = 1) 1/1 (100) 1/1 (100) 0/1 (0.0) 1/1 (100) 1/1 (100) 0/1 (0.0)
 Acinetobacter species (n = 7) 5/5 (100.0) 5/7 (71.4) 1/1 (100) 6/7 (85.7) 4/7 (57.1) 0/1 (0.0) 2/3 (66.7) 5/5 (100) 5/5 (100) 5/7 (71.4) 5/6 (83.3)
 Pseudomonas aeruginosa (n = 10) 0/8 (0.0) 0/6 (0.0) 0/6 (0.0)
  AMP CRX AUG GEN ERY CLO VAN COT TET
Gram positives (n = 40) b10/37 (27.7) b10/39 (25.6) a2/3 (66.7) b6/36 (16.7) 3/34 (8.8) 0/4 (0.0) 4/32 (12.5) b2/12 (16.6) b2/5 (40.0)
  Enterococcus species (n = 2) 1/1 (100.0) 1/1 (100.0) 2/2 (100.0) 1/1 (100) 0/1 (0.0) 0/1 (0.0)
  Staphylococcus aureus (n = 4) 3/3 (100.0) 2/4 (50.0) 0/1 (0.0) 0/4 (0.0) 1/3 (33.3) 0/4 (0.0) 0/1 (0.0) 1/1 (100) 2/3 (66.7)
  Staphylococcus epidermidis (n = 28) 2/28 (7.1) 2/28 (7.1) 2/28 (7.1) 1/28 (3.5) 2/28 (7.1) 1/10 (10.0) 0/1 (0.0)
  Streptococcus species (n = 6) 4/5 (80.0) 5/6 (83.3) 2/2 (100) 2/2 (100.0) 0/2 (0.0) 2/2 (100)
  1. Numbers with differing superscripts between Gram-positives and Gram negatives within an antimicrobial agent are significantly different at the p < 0.05
  2. AMP ampicillin, CRX cefuroxime, AUG amoxicillin/clavulanate, GEN gentamicin, AMK amikacin, CIP ciprofloxacin, LEV levofloxacin, COT cotrimoxazole, TET tetracycline, CTX cefotaxime, CHL chloramphenicol