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Table 3 Antibiotic susceptibility of blood culture isolates from cancer patients at KBTH

From: Bloodstream infections in patients with malignancies: implications for antibiotic treatment in a Ghanaian tertiary setting

Microorganisms

Resistance to antimicrobial agents (%)

AMP

CRX

AUG

GEN

AMK

CIP

LEV

COT

TET

CTX

CHL

Gram negatives (n = 49)

a33/33 (100.0)

a28/36 (77.7)

a4/5 (80.0)

a15/39 (39.5)

13/38 (34.2)

7/18 (38.8)

4/17 (23.5)

a30/33 (90.9)

a28/30 (93.3)

25/41 (60.9)

25/29 (86.2)

 Enterobacteriaceae (n = 32)

28/28 (100.0)

23/29 (79.3)

3/4 (75.0)

9/24 (42.8)

9/31 (29.0)

7/11 (63.6)

2/8 (40.0)

25/28 (89.9)

24/25 (96.0)

20/32 (62.5)

20/23 (86.9)

  Escherichia coli (n = 8)

7/7 (100.0)

4/5 (80.0)

1/1 (100)

3/8 (37.5)

4/7 (57.1)

4/5 (80.0)

0/2 (0.0)

6/6 (100)

5/6 (83.3)

4/8 (50.0)

6/6 (100)

  K. pneumoniae (n = 3)

3/3 (100.0)

2/3 (66.7)

2/3 (66.7)

0/3 (0.0)

1/1 (100)

0/1 (0.0)

3/3 (100)

3/3 (100)

3/3 (100)

3/3 (100)

  Citrobacter species (n = 12)

9/9 (100.0)

9/12 (75.0)

0/1 (0.0)

4/12 (33.3)

3/12 (25.0)

0/1 (0.0)

1/3 (33.3)

8/11 (72.7)

10/10 (100)

7/12 (63.6)

7/10 (70.0)

  Enterobacter species (n = 7)

7/7 (100.0)

7/7 (100.0)

2/2 (100.0)

2/7 (28.7)

2/4 (50.0)

1/2 (50.0)

6/6 (100)

5/5 (100)

6/7 (85.7)

4/4 (100)

  Providencia species (n = 1)

1/1 (100)

0/1 (0.0)

0/1 (0.0)

0/1 (0.0)

1/1 (100)

0/1 (0.0)

  Salmonella typhimurium (n = 1)

1/1 (100)

1/1 (100)

0/1 (0.0)

1/1 (100)

1/1 (100)

0/1 (0.0)

 Acinetobacter species (n = 7)

5/5 (100.0)

5/7 (71.4)

1/1 (100)

6/7 (85.7)

4/7 (57.1)

0/1 (0.0)

2/3 (66.7)

5/5 (100)

5/5 (100)

5/7 (71.4)

5/6 (83.3)

 Pseudomonas aeruginosa (n = 10)

0/8 (0.0)

0/6 (0.0)

0/6 (0.0)

 

AMP

CRX

AUG

GEN

ERY

CLO

VAN

COT

TET

Gram positives (n = 40)

b10/37 (27.7)

b10/39 (25.6)

a2/3 (66.7)

b6/36 (16.7)

3/34 (8.8)

0/4 (0.0)

4/32 (12.5)

b2/12 (16.6)

b2/5 (40.0)

  Enterococcus species (n = 2)

1/1 (100.0)

1/1 (100.0)

2/2 (100.0)

1/1 (100)

0/1 (0.0)

0/1 (0.0)

  Staphylococcus aureus (n = 4)

3/3 (100.0)

2/4 (50.0)

0/1 (0.0)

0/4 (0.0)

1/3 (33.3)

0/4 (0.0)

0/1 (0.0)

1/1 (100)

2/3 (66.7)

  Staphylococcus epidermidis (n = 28)

2/28 (7.1)

2/28 (7.1)

2/28 (7.1)

1/28 (3.5)

2/28 (7.1)

1/10 (10.0)

0/1 (0.0)

  Streptococcus species (n = 6)

4/5 (80.0)

5/6 (83.3)

2/2 (100)

2/2 (100.0)

0/2 (0.0)

2/2 (100)

  1. Numbers with differing superscripts between Gram-positives and Gram negatives within an antimicrobial agent are significantly different at the p < 0.05
  2. AMP ampicillin, CRX cefuroxime, AUG amoxicillin/clavulanate, GEN gentamicin, AMK amikacin, CIP ciprofloxacin, LEV levofloxacin, COT cotrimoxazole, TET tetracycline, CTX cefotaxime, CHL chloramphenicol