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Table 2 Mean proliferation indexes of benign and malignant adrenal pheochromocytoma

From: Pheochromocytoma multisystem crisis treated with emergency surgery: a case report and literature review

Benign

 N

23b

16

93

21

20

41

44

14

 PI (%)

1

0.75

0.21

0.9

<1

0.8

<1

2.2

Malignant

 N

10

15

36

4

3c

43

5

11

7

 PI (%)

5

13.9

3.0

4.3

<1

7.8

1.4

14.1

 Cut-offa

>3

≥3

>2.5

>5

>2

>5

Year

1998

2000

2000

2001

2003

2004

2008

2010

2012

Reference

[17]

[18]

[19]

[20]

[15]

[21]

[22]

[16]

[23]

  1. PI proliferation index
  2. aCut-off of PI (%) between benign and malignant pheochromocytoma
  3. bIncluding extra-adrenal tumors
  4. cPatients without metastasis at diagnosis