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Table 2 Mean proliferation indexes of benign and malignant adrenal pheochromocytoma

From: Pheochromocytoma multisystem crisis treated with emergency surgery: a case report and literature review

Benign
 N 23b 16 93 21 20 41 44 14
 PI (%) 1 0.75 0.21 0.9 <1 0.8 <1 2.2
Malignant
 N 10 15 36 4 3c 43 5 11 7
 PI (%) 5 13.9 3.0 4.3 <1 7.8 1.4 14.1
 Cut-offa >3 ≥3 >2.5 >5 >2 >5
Year 1998 2000 2000 2001 2003 2004 2008 2010 2012
Reference [17] [18] [19] [20] [15] [21] [22] [16] [23]
  1. PI proliferation index
  2. aCut-off of PI (%) between benign and malignant pheochromocytoma
  3. bIncluding extra-adrenal tumors
  4. cPatients without metastasis at diagnosis