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Fig. 2 | BMC Research Notes

Fig. 2

From: A cancer cell-line titration series for evaluating somatic classification

Fig. 2

Precision and recall performance of the somatic callers at each cellularity. The 7 data points for each tool are represented by pie charts which correspond to the different cellularities (from 5 % tumour to 100 % tumour). The data points for a caller with perfect performance would be in the top right corner of the plot, indicating that all verified SNVs were called, and no false calls were made. Input to the callers was created by aligning with Novoalign and collapsing duplicate reads. Realignment or recalibration with GATK was not performed. Note the high performance of MuTect and Strelka

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