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Table 1 Description of Maffucci patients with or without neoplasms worldwide

From: Maffucci syndrome and neoplasms: a case report and review of the literature

Number of patients with Maffucci syndrome Number of osteosarcoma cases Number of non-skeletal neoplasms Kind of non-skeletal neoplasms Follow-up Year of publication References
1 1 probably malignant transformation of a clavicular lesion 0   No 1881 [11]
0 Astrocytoma, pituitary adenomas, juvenile granulosa cell tumor   1973 [12]
7 4 (three of them had two neoplasms each) 3 BC, PC, astrocytoma Yes 1987 [8]
1 0 1 Astrocytoma   1987 [13]
1 0 1 Astrocytoma   1990 [14]
1 0 1 Ovarian fibrosarcoma No 1990 [15]
1 0 1 Astrocytoma   1991 [16]
1 0 0   No 2001 [17]
17 9/17 (53 %) 0   Yes 2011 [10]
1 1 1 Hemangioendothelioma Yes 2012 [18]
1 1 0   No 2012 [19]
1 0 1 Spindle cell hemangioma No 2013 [20]
1 1 0   No 2013 [11]
1 0 0   No 2013 [21]
1 0 1 Anaplastic astrocytoma No 2014 [22]
1 1 0   No 2014 [23]
1 0 0   No 2014 [24]
1 1 0   No 2014 [25]
1 1 0   No 2014 [26]
9 1 1 Acute myeloid leukemia and von Willebrand disease No 2014 [27]
1 1 0   No 2015 [28]
1 1 0   No 2015 [29]
1 1 0   No 2015 [30]
1 0 0   No 2015 [31]
  1. PC pancreatic cancer, BC biliary adenocarcinoma
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