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Table 1 Description of Maffucci patients with or without neoplasms worldwide

From: Maffucci syndrome and neoplasms: a case report and review of the literature

Number of patients with Maffucci syndrome

Number of osteosarcoma cases

Number of non-skeletal neoplasms

Kind of non-skeletal neoplasms

Follow-up

Year of publication

References

1

1 probably malignant transformation of a clavicular lesion

0

 

No

1881

[11]

0

3 

Astrocytoma, pituitary adenomas, juvenile granulosa cell tumor

 

1973

[12]

7

4 (three of them had two neoplasms each)

3

BC, PC, astrocytoma

Yes

1987

[8]

1

0

1

Astrocytoma

 

1987

[13]

1

0

1

Astrocytoma

 

1990

[14]

1

0

1

Ovarian fibrosarcoma

No

1990

[15]

1

0

1

Astrocytoma

 

1991

[16]

1

0

0

 

No

2001

[17]

17

9/17 (53 %)

0

 

Yes

2011

[10]

1

1

1

Hemangioendothelioma

Yes

2012

[18]

1

1

0

 

No

2012

[19]

1

0

1

Spindle cell hemangioma

No

2013

[20]

1

1

0

 

No

2013

[11]

1

0

0

 

No

2013

[21]

1

0

1

Anaplastic astrocytoma

No

2014

[22]

1

1

0

 

No

2014

[23]

1

0

0

 

No

2014

[24]

1

1

0

 

No

2014

[25]

1

1

0

 

No

2014

[26]

9

1

1

Acute myeloid leukemia and von Willebrand disease

No

2014

[27]

1

1

0

 

No

2015

[28]

1

1

0

 

No

2015

[29]

1

1

0

 

No

2015

[30]

1

0

0

 

No

2015

[31]

  1. PC pancreatic cancer, BC biliary adenocarcinoma