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Table 2 CSF profiles and imaging findings

From: Normocellular CSF in herpes simplex encephalitis

CSF Profile CSF pleocytosis group (WBC > 5cells/mm3) Normocellular CSF group (WBC ≤ 5cells/mm3)
Days of CSF examination after neurological onset Day 0—1: 5 (29.4 %)
Day 2—10: 12 (70.6 %)
Day 0—1: 1 (16.7 %)
Day 2—10: 5 (83.3 %)
CSF protein 0–60 mg/dl: 1 (6.3 %)
61–100 mg/dl: 7 (43.8 %)
>100 mg/dl: 8 (50 %)
Not available: 1
0–60 mg/dl: 2 (33.3 %)
61–100 mg/dl: 4 (66.7 %)
>100 mg/dl: 0
CSF glucose <30 mg/dl: 1 (6.3 %)
31–60 mg/dl: 7 (43.8 %)
>60 mg/dl: 8 (50 %)
Not available: 1
<30 mg/dl: 0
31–60 mg/dl 1 (16.7 %)
>60 mg/dl: 5 (83.3 %)
Average CSF viral load 12,200 copies/ml (39–11,755,813 copies/ml) (11 cases available: 6 had qualitative test) 3027 copies/ml
(59–5970 copies/ml)
(4 cases available: 3 had qualitative test)
Brain imaging findings 16 available records 6 available records
 Predominant temporal lobe lesions 5 (29.4 %) 1 (16.7 %)
 Fronto-temporal lesions 4 (23.5 %) 1 (16.7 %)
 Other cortical and subcortical lesions (non fronto-temporal)a 3 (18.8 %) 0
 Fronto-temporal and thalamic lesionsa 3 (18.8 %) 0
 Normal or Miscellaneousb 0 2 (33.3 %)
 Normal CT (MRI not performed) 1 (5.9 %) 2 (33.3 %)
  1. aTwo of the patients (a non fronto-temporal lesion and one with fronto-temporal and thalamic lesions) also had vasculitis, visualized using magnetic resonance angiography
  2. bMiscellaneous refers to non-specific lesions such as non-specific white matter changes, aging brain etc