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Table 2 Change in anxiety during treatment (mITT population)

From: Adherence to interferon β-1a therapy using an electronic self-injector in multiple sclerosis: a multicentre, single-arm, observational, phase IV study

Measure Baseline Week 12 Week 24
Hospital anxiety and depression scale
 Anxiety subscale score
(range 0–21)
7.0 ± 4.1 5.8 ± 4.3* 5.9 ± 4.1*
State–trait anxiety inventory
 State anxiety subscale
(range 20–80)
40.4 ± 12.3 35.9 ± 12.7* 36.6 ± 12.9*
 Trait anxiety subscale
(range 20–80)
38.8 ± 10.9 36.7 ± 12.1* 37.6 ± 12.1
  1. * p < 0.005 by comparison to baseline, as calculated by a paired t-test
  2. mITT modified intent-to-treat